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morphine, amethocaine
Morphine is a potent opioid agonist that binds to opioid receptors in the brain, spinal cord, and other areas to produce analgesia and euphoria.
Morphine is a potent opioid agonist that binds to opioid receptors in the brain, spinal cord, and other areas to produce analgesia and euphoria. Used for Pain management in cancer patients, Pain management in acute injuries.
At a glance
| Generic name | morphine, amethocaine |
|---|---|
| Sponsor | The Hospital for Sick Children |
| Drug class | opioid |
| Target | mu-opioid receptor |
| Modality | Small molecule |
| Therapeutic area | Pain management |
| Phase | Phase 3 |
Mechanism of action
Morphine works by activating the mu-opioid receptor, which is responsible for the analgesic and euphoric effects. This activation also leads to the release of endogenous opioids, which can contribute to the development of tolerance and dependence.
Approved indications
- Pain management in cancer patients
- Pain management in acute injuries
Common side effects
- Nausea
- Vomiting
- Constipation
- Dizziness
- Respiratory depression
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |