Last reviewed 2026-04-22 · How we verify

Mix-and-Match PanOptix/Vivity

A mix-and-match intraocular lens combination that pairs PanOptix and Vivity multifocal/extended depth of focus technologies to optimize vision across multiple distances.

A mix-and-match intraocular lens combination that pairs PanOptix and Vivity multifocal/extended depth of focus technologies to optimize vision across multiple distances. Used for Cataract surgery with presbyopia correction in patients desiring multifocal or extended depth of focus vision.

At a glance

Mechanism of action

This approach combines two different presbyopia-correcting lens designs in a single eye or bilaterally to leverage the strengths of each technology. PanOptix uses trifocal diffractive optics for near, intermediate, and distance vision, while Vivity uses extended depth of focus technology. The combination aims to provide superior visual outcomes across the full range of distances while minimizing unwanted optical effects like halos or glare.

Approved indications

• Cataract surgery with presbyopia correction in patients desiring multifocal or extended depth of focus vision

Common side effects

• Glare or halos
• Reduced contrast sensitivity
• Dysphotopsia
• Posterior capsular opacification

Key clinical trials

• A Prospective, Randomized, Subject and Vision-assessor Masked, Multicenter Study Comparing Bilateral Clareon PanOptix, Bilateral Clareon PanOptix Pro, and Mixed Clareon PanOptix Pro/Vivity Intraocular Lens Implantation in Cataract Subjects (PHASE4)

Primary sources

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Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

• Mix-and-Match PanOptix/Vivity CI brief — competitive landscape report
• Mix-and-Match PanOptix/Vivity updates RSS · CI watch RSS
• Berkeley Eye Center portfolio CI