{"id":"mix-and-match-panoptix-vivity","safety":{"commonSideEffects":[{"rate":null,"effect":"Glare or halos"},{"rate":null,"effect":"Reduced contrast sensitivity"},{"rate":null,"effect":"Dysphotopsia"},{"rate":null,"effect":"Posterior capsular opacification"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This approach combines two different presbyopia-correcting lens designs in a single eye or bilaterally to leverage the strengths of each technology. PanOptix uses trifocal diffractive optics for near, intermediate, and distance vision, while Vivity uses extended depth of focus technology. The combination aims to provide superior visual outcomes across the full range of distances while minimizing unwanted optical effects like halos or glare.","oneSentence":"A mix-and-match intraocular lens combination that pairs PanOptix and Vivity multifocal/extended depth of focus technologies to optimize vision across multiple distances.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-27T23:55:29.765Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Cataract surgery with presbyopia correction in patients desiring multifocal or extended depth of focus vision"}]},"trialDetails":[{"nctId":"NCT06922084","phase":"PHASE4","title":"A Prospective, Randomized, Subject and Vision-assessor Masked, Multicenter Study Comparing Bilateral Clareon PanOptix, Bilateral Clareon PanOptix Pro, and Mixed Clareon PanOptix Pro/Vivity Intraocular Lens Implantation in Cataract Subjects","status":"RECRUITING","sponsor":"Berkeley Eye Center","startDate":"2025-03-17","conditions":"Cataract","enrollment":320}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Mix-and-Match PanOptix/Vivity","genericName":"Mix-and-Match PanOptix/Vivity","companyName":"Berkeley Eye Center","companyId":"berkeley-eye-center","modality":"Small molecule","firstApprovalDate":"","aiSummary":"A mix-and-match intraocular lens combination that pairs PanOptix and Vivity multifocal/extended depth of focus technologies to optimize vision across multiple distances. Used for Cataract surgery with presbyopia correction in patients desiring multifocal or extended depth of focus vision.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}