Last reviewed 2026-05-27 · How we verify

Miralax-Gatorade Prep

VA Office of Research and Development · FDA-approved active Small molecule ✓ Verified May 2026

Miralax-Gatorade Prep is a Osmotic laxative bowel preparation agent Small molecule drug developed by VA Office of Research and Development. It is currently FDA-approved for Bowel preparation prior to colonoscopy or other gastrointestinal procedures.

Miralax-Gatorade Prep is an osmotic laxative combined with an electrolyte solution that draws water into the bowel to promote bowel evacuation.

Miralax-Gatorade Prep is a bowel preparation used for colonoscopy, specifically studied in children for colonoscopy and colorectal cancer screening. It contains polyethylene glycol 3350 as its active ingredient, which is a type of laxative.

At a glance

Generic name	Miralax-Gatorade Prep
Sponsor	VA Office of Research and Development
Drug class	Osmotic laxative bowel preparation agent
Modality	Small molecule
Therapeutic area	Gastroenterology
Phase	FDA-approved

Mechanism of action

Polyethylene glycol (Miralax) acts as an osmotic agent that retains water in the intestinal lumen, increasing stool bulk and promoting peristalsis. The Gatorade component provides electrolytes and fluid to maintain hydration and electrolyte balance during bowel preparation. Together, they facilitate complete bowel cleansing prior to colonoscopy or other procedures.

Approved indications

Bowel preparation prior to colonoscopy or other gastrointestinal procedures

Common side effects

Nausea
Bloating
Abdominal discomfort
Vomiting

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Source	Used for
ClinicalTrials.gov	Trial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Miralax-Gatorade Prep CI brief — competitive landscape report
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VA Office of Research and Development portfolio CI

Frequently asked questions about Miralax-Gatorade Prep

What is Miralax-Gatorade Prep?

Miralax-Gatorade Prep is a Osmotic laxative bowel preparation agent drug developed by VA Office of Research and Development, indicated for Bowel preparation prior to colonoscopy or other gastrointestinal procedures.

How does Miralax-Gatorade Prep work?

Miralax-Gatorade Prep is an osmotic laxative combined with an electrolyte solution that draws water into the bowel to promote bowel evacuation.

What is Miralax-Gatorade Prep used for?

Miralax-Gatorade Prep is indicated for Bowel preparation prior to colonoscopy or other gastrointestinal procedures.

Who makes Miralax-Gatorade Prep?

Miralax-Gatorade Prep is developed and marketed by VA Office of Research and Development (see full VA Office of Research and Development pipeline at /company/va-office-of-research-and-development).

What drug class is Miralax-Gatorade Prep in?

Miralax-Gatorade Prep belongs to the Osmotic laxative bowel preparation agent class. See all Osmotic laxative bowel preparation agent drugs at /class/osmotic-laxative-bowel-preparation-agent.

What development phase is Miralax-Gatorade Prep in?

Miralax-Gatorade Prep is FDA-approved (marketed).

What are the side effects of Miralax-Gatorade Prep?

Common side effects of Miralax-Gatorade Prep include Nausea, Bloating, Abdominal discomfort, Vomiting.

Drug class: All Osmotic laxative bowel preparation agent drugs
Manufacturer: VA Office of Research and Development — full pipeline
Therapeutic area: All drugs in Gastroenterology
Indication: Drugs for Bowel preparation prior to colonoscopy or other gastrointestinal procedures

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing