Last reviewed · How we verify
Vialin (MEPHENTERMINE)
Vialin, a mephentermine product marketed by Baxter, is indicated for hypotension secondary to spinal anesthesia and faces competition from several same-class drugs, including off-patent options like dopamine and dobutamine. Its mechanism of action through the alpha-1A adrenergic receptor provides a targeted approach to increasing blood pressure, distinguishing it in the treatment of perioperative hypotension. The primary risk to Vialin's market position is the presence of multiple generic competitors and the upcoming key composition patent expiry in 2028.
At a glance
| Generic name | MEPHENTERMINE |
|---|---|
| Sponsor | Baxter |
| Drug class | Indirectly Acting Sympathomimetic Amines |
| Target | Alpha-1A adrenergic receptor |
| Modality | Small molecule |
| Therapeutic area | Hematology |
| Phase | FDA-approved |
| First approval | 1951 |
Approved indications
- Hypotension Secondary to Spinal Anesthesia
- Low blood pressure
- Prevention of Hypotension During Spinal Anesthesia
Common side effects
Drug interactions
- pargyline
- phenelzine
- tranylcypromine
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| FDA label | Mechanism, indications, dosing, boxed warnings, drug interactions |
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Vialin CI brief — competitive landscape report
- Vialin updates RSS · CI watch RSS
- Baxter portfolio CI