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Melatonin2%gel
Melatonin is a topical gel formulation that acts as a free radical scavenger and antioxidant to protect skin and promote wound healing.
Melatonin is a topical gel formulation that acts as a free radical scavenger and antioxidant to protect skin and promote wound healing. Used for Wound healing and tissue repair, Skin protection and antioxidant therapy.
At a glance
| Generic name | Melatonin2%gel |
|---|---|
| Also known as | intra- pocket Melatonin gel |
| Sponsor | Al-Azhar University |
| Drug class | Topical antioxidant |
| Target | Free radicals / reactive oxygen species |
| Modality | Small molecule |
| Therapeutic area | Dermatology |
| Phase | FDA-approved |
Mechanism of action
Melatonin functions as a potent antioxidant that neutralizes reactive oxygen species and reduces oxidative stress in skin tissue. When applied topically as a 2% gel, it may promote tissue repair, reduce inflammation, and protect against UV-induced damage. The mechanism leverages melatonin's natural antioxidant properties to support dermatological healing and skin health.
Approved indications
- Wound healing and tissue repair
- Skin protection and antioxidant therapy
Common side effects
- Local skin irritation
- Contact dermatitis
Key clinical trials
- Evaluation Efficacy of Melatonin Gel as Adjunctive Therapy in Chronic Periodontitis (PHASE4)
- The Effect of Melatonin Application Following Removal of Impacted Third Molar (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |