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MCT/LCT containing lipid emulsion
A lipid emulsion combining medium-chain triglycerides (MCT) and long-chain triglycerides (LCT) that provides essential fatty acids and calories for parenteral nutrition.
A lipid emulsion combining medium-chain triglycerides (MCT) and long-chain triglycerides (LCT) that provides essential fatty acids and calories for parenteral nutrition. Used for Parenteral nutrition in patients unable to receive adequate oral or enteral nutrition, Provision of essential fatty acids and calories in critically ill or post-operative patients.
At a glance
| Generic name | MCT/LCT containing lipid emulsion |
|---|---|
| Sponsor | B. Braun Melsungen AG |
| Drug class | Lipid emulsion for parenteral nutrition |
| Modality | Small molecule |
| Therapeutic area | Nutrition support / Critical care |
| Phase | Phase 3 |
Mechanism of action
MCT/LCT lipid emulsions are used in intravenous nutrition to deliver both rapidly metabolizable medium-chain fatty acids and essential long-chain polyunsaturated fatty acids. MCTs are more readily oxidized for energy, while LCTs provide essential linoleic and alpha-linolenic acids necessary for cellular function and membrane integrity. This combination formulation aims to optimize both energy delivery and essential nutrient provision in patients unable to receive adequate oral or enteral nutrition.
Approved indications
- Parenteral nutrition in patients unable to receive adequate oral or enteral nutrition
- Provision of essential fatty acids and calories in critically ill or post-operative patients
Common side effects
- Hypertriglyceridemia
- Infusion site reactions
- Hepatic steatosis
- Thrombophlebitis
- Allergic reactions
Key clinical trials
- The HOME Study (HPN With OMEGA-3) (PHASE4)
- Comparison of Two Different Lipid Emulsions for Parenteral Nutrition in Preterm Infants (PHASE2)
- Different Lipid Emulsions in Acute Lung Injury Patients (PHASE4)
- Effects Of Fish Oil Emulsion On Severe Acute Pancreatitis Patients (PHASE2)
- Efficacy and Safety of a Fish Oil Containing Lipid Emulsion (PHASE3)
- Pure Fish Oil Parenteral Lipid Emulsion in Patients With Gastrointestinal Cancer (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- MCT/LCT containing lipid emulsion CI brief — competitive landscape report
- MCT/LCT containing lipid emulsion updates RSS · CI watch RSS
- B. Braun Melsungen AG portfolio CI