{"id":"mct-lct-containing-lipid-emulsion","safety":{"commonSideEffects":[{"rate":null,"effect":"Hypertriglyceridemia"},{"rate":null,"effect":"Infusion site reactions"},{"rate":null,"effect":"Hepatic steatosis"},{"rate":null,"effect":"Thrombophlebitis"},{"rate":null,"effect":"Allergic reactions"}]},"_chembl":{"chemblId":"CHEMBL3354642","moleculeType":"Small molecule","molecularWeight":"1826.45"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"MCT/LCT lipid emulsions are used in intravenous nutrition to deliver both rapidly metabolizable medium-chain fatty acids and essential long-chain polyunsaturated fatty acids. MCTs are more readily oxidized for energy, while LCTs provide essential linoleic and alpha-linolenic acids necessary for cellular function and membrane integrity. This combination formulation aims to optimize both energy delivery and essential nutrient provision in patients unable to receive adequate oral or enteral nutrition.","oneSentence":"A lipid emulsion combining medium-chain triglycerides (MCT) and long-chain triglycerides (LCT) that provides essential fatty acids and calories for parenteral nutrition.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T00:49:44.293Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Parenteral nutrition in patients unable to receive adequate oral or enteral nutrition"},{"name":"Provision of essential fatty acids and calories in critically ill or post-operative patients"}]},"trialDetails":[{"nctId":"NCT03282955","phase":"PHASE4","title":"The HOME Study (HPN With OMEGA-3)","status":"COMPLETED","sponsor":"B. Braun Melsungen AG","startDate":"2018-01-08","conditions":"Patients Requiring Home Parenteral Nutrition","enrollment":74},{"nctId":"NCT00497289","phase":"PHASE2","title":"Comparison of Two Different Lipid Emulsions for Parenteral Nutrition in Preterm Infants","status":"COMPLETED","sponsor":"B. Braun Melsungen AG","startDate":"2006-01","conditions":"Preterm Infants, Parenteral Nutrition n-3 Fatty Acids","enrollment":48},{"nctId":"NCT01814956","phase":"PHASE4","title":"Different Lipid Emulsions in Acute Lung Injury Patients","status":"TERMINATED","sponsor":"B. Braun Melsungen AG","startDate":"2013-03","conditions":"Parenteral Nutrition","enrollment":1},{"nctId":"NCT01745861","phase":"PHASE2","title":"Effects Of Fish Oil Emulsion On Severe Acute Pancreatitis Patients","status":"COMPLETED","sponsor":"University Hospitals, Leicester","startDate":"2010-06","conditions":"Assess Effect of Omega-3 Fish Oil in Patients With Severe Acute Pancreatitis","enrollment":44},{"nctId":"NCT01176695","phase":"PHASE3","title":"Efficacy and Safety of a Fish Oil Containing Lipid Emulsion","status":"COMPLETED","sponsor":"B. Braun Melsungen AG","startDate":"2010-04","conditions":"Parenteral Nutrition","enrollment":240},{"nctId":"NCT01218841","phase":"PHASE2","title":"Pure Fish Oil Parenteral Lipid Emulsion in Patients With Gastrointestinal Cancer","status":"COMPLETED","sponsor":"University of Sao Paulo","startDate":"2005-11","conditions":"Surgery","enrollment":85}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":2,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"MCT/LCT containing lipid emulsion","genericName":"MCT/LCT containing lipid emulsion","companyName":"B. Braun Melsungen AG","companyId":"b-braun-melsungen-ag","modality":"Small molecule","firstApprovalDate":"","aiSummary":"A lipid emulsion combining medium-chain triglycerides (MCT) and long-chain triglycerides (LCT) that provides essential fatty acids and calories for parenteral nutrition. Used for Parenteral nutrition in patients unable to receive adequate oral or enteral nutrition, Provision of essential fatty acids and calories in critically ill or post-operative patients.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}