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Matching placebo to Quetiapine XR
Matching placebo to Quetiapine XR is a Small molecule drug developed by Janssen Research & Development, LLC. It is currently in Phase 3 development for Control arm in Phase 3 clinical trials of Quetiapine XR (schizophrenia, bipolar disorder, or major depressive disorder, depending on the specific trial).
This is a matching placebo formulation designed to mimic Quetiapine XR (an atypical antipsychotic) for blinded clinical trial purposes.
This is a matching placebo formulation designed to mimic Quetiapine XR (an atypical antipsychotic) for blinded clinical trial purposes. Used for Control arm in Phase 3 clinical trials of Quetiapine XR (schizophrenia, bipolar disorder, or major depressive disorder, depending on the specific trial).
At a glance
| Generic name | Matching placebo to Quetiapine XR |
|---|---|
| Sponsor | Janssen Research & Development, LLC |
| Modality | Small molecule |
| Therapeutic area | Psychiatry |
| Phase | Phase 3 |
Mechanism of action
Matching placebos are inert formulations manufactured to be identical in appearance, taste, and administration schedule to the active drug being tested, enabling double-blind study designs. In this case, the placebo matches Quetiapine XR, an extended-release atypical antipsychotic that antagonizes dopamine and serotonin receptors. The placebo itself contains no active pharmaceutical ingredient and serves as the control arm in Phase 3 trials.
Approved indications
- Control arm in Phase 3 clinical trials of Quetiapine XR (schizophrenia, bipolar disorder, or major depressive disorder, depending on the specific trial)
Common side effects
Key clinical trials
- A Study of Seltorexant Compared to Quetiapine XR as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy (PHASE3)
- Quetiapine for Bipolar Disorder and Alcohol Dependence (PHASE4)
- A Study to Compare the Efficacy, Safety, and Tolerability of JNJ-42847922 Versus Quetiapine Extended-Release as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy (PHASE2)
- Study to Evaluate the Effect and Safety of Quetiapine Extended Release (XR) (FK949E) in Major Depressive Disorder (PHASE2)
- Evaluate the Efficacy and Safety of Quetiapine Fumarate (SEROQUEL) Extended Release as Monotherapy in the Treatment of Patients With Bipolar Depression (PHASE3)
- Lurasidone HCL - A 6-week Phase 3 Study of Patients With Acute Schizophrenia. (PHASE3)
- A Study of Quetiapine SR (Seroquel SR) to Treat SSRI-Resistant, Comorbid Panic Disorder Patients (PHASE4)
- Quetiapine for the Reduction of Cocaine Use (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Matching placebo to Quetiapine XR CI brief — competitive landscape report
- Matching placebo to Quetiapine XR updates RSS · CI watch RSS
- Janssen Research & Development, LLC portfolio CI
Frequently asked questions about Matching placebo to Quetiapine XR
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Related
- Manufacturer: Janssen Research & Development, LLC — full pipeline
- Therapeutic area: All drugs in Psychiatry
- Indication: Drugs for Control arm in Phase 3 clinical trials of Quetiapine XR (schizophrenia, bipolar disorder, or major depressive disorder, depending on the specific trial)
- Compare: Matching placebo to Quetiapine XR vs similar drugs
- Pricing: Matching placebo to Quetiapine XR cost, discount & access