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Lubricant Eye Drops (Optive™)
Optive lubricates and protects the ocular surface by providing a multi-component tear substitute that mimics natural tears.
Optive lubricates and protects the ocular surface by providing a multi-component tear substitute that mimics natural tears. Used for Dry eye disease / Keratoconjunctivitis sicca, Ocular surface lubrication and protection.
At a glance
| Generic name | Lubricant Eye Drops (Optive™) |
|---|---|
| Also known as | Optive™ |
| Sponsor | Allergan |
| Drug class | Artificial tear / Lubricant |
| Modality | Small molecule |
| Therapeutic area | Ophthalmology |
| Phase | FDA-approved |
Mechanism of action
Optive is a preservative-free lubricating eye drop formulation containing carboxymethylcellulose sodium and glycerin, which work together to hydrate and coat the cornea and conjunctiva. The formulation provides sustained lubrication and protection for dry eye symptoms by reducing friction and maintaining tear film stability on the ocular surface.
Approved indications
- Dry eye disease / Keratoconjunctivitis sicca
- Ocular surface lubrication and protection
Common side effects
- Ocular irritation
- Blurred vision
- Eye discomfort
Key clinical trials
- Tear Film Stability After Instillation of Over-the-Counter (OTC) Artificial Drops (NA)
- A Study to Compare the Safety and Efficacy of A New Eye Drop Formulation With OPTIVE™ in Subjects With Dry Eye Disease (PHASE3)
- Comparative Efficacy of SYSTANE® ULTRA vs Optive™ in Improving Tear Film Break-up Time (NA)
- Evaluation of Extended Tear Film Break Up Time (TFBUT) With an Ocular Emulsion (NA)
- Efficacy and Acceptability of Two Lubricant Eye Drops (PHASE4)
- Study to Compare the Efficacy and Safety of Two Non-Preserved Artificial Tears for the Treatment of Dry Eye Signs and Symptoms (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Lubricant Eye Drops (Optive™) CI brief — competitive landscape report
- Lubricant Eye Drops (Optive™) updates RSS · CI watch RSS
- Allergan portfolio CI