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LTOT 24 h/day
LTOT 24 h/day delivers supplemental oxygen continuously throughout the day and night to maintain adequate blood oxygen levels in patients with chronic hypoxemia.
LTOT 24 h/day delivers supplemental oxygen continuously throughout the day and night to maintain adequate blood oxygen levels in patients with chronic hypoxemia. Used for Chronic obstructive pulmonary disease (COPD) with chronic hypoxemia, Interstitial lung disease with chronic hypoxemia, Other chronic respiratory conditions requiring continuous oxygen supplementation.
At a glance
| Generic name | LTOT 24 h/day |
|---|---|
| Also known as | Long-term oxygen therapy prescribed continuously (24 h/day) |
| Sponsor | Skane University Hospital |
| Modality | Small molecule |
| Therapeutic area | Respiratory/Pulmonary |
| Phase | FDA-approved |
Mechanism of action
Long-term oxygen therapy (LTOT) is a supportive treatment that increases inspired oxygen concentration to correct chronic hypoxemia (low blood oxygen). By delivering oxygen 24 hours daily, it reduces the work of breathing, decreases pulmonary vasoconstriction, and helps prevent secondary complications such as pulmonary hypertension and cor pulmonale in patients with chronic respiratory diseases.
Approved indications
- Chronic obstructive pulmonary disease (COPD) with chronic hypoxemia
- Interstitial lung disease with chronic hypoxemia
- Other chronic respiratory conditions requiring continuous oxygen supplementation
Common side effects
- Nasal dryness and irritation
- Skin breakdown from oxygen delivery device
- Oxygen toxicity (with prolonged high concentrations)
- Fire hazard risk
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- LTOT 24 h/day CI brief — competitive landscape report
- LTOT 24 h/day updates RSS · CI watch RSS
- Skane University Hospital portfolio CI