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Lorcam (LORNOXICAM)
Lorcam works by blocking the COX-2 enzyme, which reduces the production of prostaglandins that cause pain and inflammation.
Lorcam, also known as Lornoxicam, is a small molecule nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class. It is used to treat pain, but its target is unknown. Lorcam is not FDA approved, and its commercial status is unclear. Key safety considerations include its low bioavailability of 1%, which may impact its efficacy. As a nonsteroidal anti-inflammatory drug, Lorcam works by inhibiting the enzyme COX-2, which is involved in the production of prostaglandins that cause pain and inflammation.
At a glance
| Generic name | LORNOXICAM |
|---|---|
| Drug class | lornoxicam |
| Modality | Small molecule |
| Therapeutic area | Pain |
| Phase | discontinued |
Mechanism of action
Imagine your body has a factory that produces chemicals called prostaglandins, which can cause pain and swelling. Lorcam blocks the machine that makes these chemicals, so the pain and swelling go away. This helps to relieve pain and reduce inflammation.
Approved indications
- Pain
Common side effects
- Drug interaction
- Rebound effect
- Angioedema
- Tick-borne viral encephalitis
Key clinical trials
- Efficacy of Chemically Distinct Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) and Pain Phenotypes in Adhesive Capsulitis (NA)
- Laparoscopic Cholecystectomy and Quality of Recovery (NA)
- The Effect of Methylene Blue Infiltrating Injection on Anal Pain After Milligan-Morgan Surgery: a Randomized Controlled Clinical Study (PHASE3)
- Lornoxicam Versus Etodolac After Third Molar Surgery (PHASE4)
- Efficacy of iPACK After Unilateral TKA (NA)
- Continuous Lornoxicam Infusion for Orthopaedic Surgery (PHASE1,PHASE2)
- Perineural Low-dose Dexamethasone Added to Infraclavicular Block Anesthesia (PHASE3)
- Lornoxicam With Low Dose Ketamine Versus Pethidine to Control Pain of Acute Renal Colic (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Lorcam CI brief — competitive landscape report
- Lorcam updates RSS · CI watch RSS