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lipoic acid and omega-3 fatty acids

Oregon Health and Science University · FDA-approved active Small molecule

lipoic acid and omega-3 fatty acids is a Nutritional supplement combination Small molecule drug developed by Oregon Health and Science University. It is currently FDA-approved for Cognitive decline and neuroprotection (investigational/marketed as supplement). Also known as: thiotic acid, fish oil, fish oil concentrate.

Lipoic acid and omega-3 fatty acids work together to reduce oxidative stress and inflammation through antioxidant and anti-inflammatory pathways.

Lipoic acid and omega-3 fatty acids work together to reduce oxidative stress and inflammation through antioxidant and anti-inflammatory pathways. Used for Cognitive decline and neuroprotection (investigational/marketed as supplement).

At a glance

Generic namelipoic acid and omega-3 fatty acids
Also known asthiotic acid, fish oil, fish oil concentrate
SponsorOregon Health and Science University
Drug classNutritional supplement combination
ModalitySmall molecule
Therapeutic areaNeurology / Metabolic disorders
PhaseFDA-approved

Mechanism of action

Lipoic acid is a mitochondrial cofactor that acts as a potent antioxidant, scavenging free radicals and regenerating other antioxidants like vitamins C and E. Omega-3 fatty acids (EPA and DHA) reduce inflammatory mediators and support cellular membrane integrity. Together, they may improve metabolic function and reduce neuroinflammation.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

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Frequently asked questions about lipoic acid and omega-3 fatty acids

What is lipoic acid and omega-3 fatty acids?

lipoic acid and omega-3 fatty acids is a Nutritional supplement combination drug developed by Oregon Health and Science University, indicated for Cognitive decline and neuroprotection (investigational/marketed as supplement).

How does lipoic acid and omega-3 fatty acids work?

Lipoic acid and omega-3 fatty acids work together to reduce oxidative stress and inflammation through antioxidant and anti-inflammatory pathways.

What is lipoic acid and omega-3 fatty acids used for?

lipoic acid and omega-3 fatty acids is indicated for Cognitive decline and neuroprotection (investigational/marketed as supplement).

Who makes lipoic acid and omega-3 fatty acids?

lipoic acid and omega-3 fatty acids is developed and marketed by Oregon Health and Science University (see full Oregon Health and Science University pipeline at /company/oregon-health-and-science-university).

Is lipoic acid and omega-3 fatty acids also known as anything else?

lipoic acid and omega-3 fatty acids is also known as thiotic acid, fish oil, fish oil concentrate.

What drug class is lipoic acid and omega-3 fatty acids in?

lipoic acid and omega-3 fatty acids belongs to the Nutritional supplement combination class. See all Nutritional supplement combination drugs at /class/nutritional-supplement-combination.

What development phase is lipoic acid and omega-3 fatty acids in?

lipoic acid and omega-3 fatty acids is FDA-approved (marketed).

What are the side effects of lipoic acid and omega-3 fatty acids?

Common side effects of lipoic acid and omega-3 fatty acids include Gastrointestinal upset, Mild headache, Skin rash (lipoic acid).

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