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Lemongrass Oil
Lemongrass oil contains volatile compounds (citral, geraniol, limonene) that exhibit antimicrobial, anti-inflammatory, and antioxidant properties through multiple cellular pathways.
Lemongrass oil contains volatile compounds (citral, geraniol, limonene) that exhibit antimicrobial, anti-inflammatory, and antioxidant properties through multiple cellular pathways. Used for Traditional use for digestive complaints and inflammation, Antimicrobial applications in traditional medicine.
At a glance
| Generic name | Lemongrass Oil |
|---|---|
| Sponsor | Suez Canal University |
| Drug class | Herbal extract / Essential oil |
| Modality | Small molecule |
| Therapeutic area | Antimicrobial, Anti-inflammatory, Antioxidant |
| Phase | FDA-approved |
Mechanism of action
The essential oil from Cymbopogon citratus contains bioactive terpenes that inhibit microbial growth, reduce inflammatory cytokine production, and scavenge free radicals. These compounds may modulate cellular signaling pathways involved in inflammation and oxidative stress, though the exact molecular targets vary depending on the specific bioactive constituent and cell type.
Approved indications
- Traditional use for digestive complaints and inflammation
- Antimicrobial applications in traditional medicine
- Antioxidant support (marketed/traditional use)
Common side effects
- Allergic contact dermatitis
- Gastrointestinal upset (with ingestion)
- Photosensitivity (potential)
Key clinical trials
- Patient-preferred Aromatherapy Versus Placebo For Reducing Preoperative Anxiety In Patients Undergoing Eye Surgery (NA)
- Assessing the Efficacy of Lemongrass and Lavender Aromatherapy in Reducing Dental Anxiety and Pain Associated With Local Anesthetic Injections in Pediatric Dental Patients (PHASE4)
- A Single-Group Study to Examine the Efficacy of a Melatonin Lotion With Magnesium to Improve Sleep Quality and Quantity (NA)
- Premenstrual Symptoms and Aromatherapy (NA)
- The Impact of Aromatherapy on Alleviating Dental Anxiety in Children (NA)
- To Study the Healing Effect of 0.25% Lemongrass Oil Mouthwash on Chronic Periodontitis Patients.
- An Open-label Study Evaluating the Effectiveness of CGB-400 Topical Gel for Fungal Infection
- Cymbopogon Citratus Gel as Local Drug Delivery Agent in Reducing Matrix Metalloproteinase-8 Levels Intra-crevicularly in the Treatment of Stage II Periodontitis (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Lemongrass Oil CI brief — competitive landscape report
- Lemongrass Oil updates RSS · CI watch RSS
- Suez Canal University portfolio CI