{"id":"lemongrass-oil","safety":{"commonSideEffects":[{"rate":null,"effect":"Allergic contact dermatitis"},{"rate":null,"effect":"Gastrointestinal upset (with ingestion)"},{"rate":null,"effect":"Photosensitivity (potential)"}]},"_chembl":null,"_dailymed":{"setId":"46a6119c-2da5-496c-8a59-978c49c54756","title":"REPELLENT (CASTOR OIL, WEST INDIAN LEMONGRASS OIL, PEPPERMINT OIL AND ROSEMARY OIL) STICK [ONA STICK USA LLC]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The essential oil from Cymbopogon citratus contains bioactive terpenes that inhibit microbial growth, reduce inflammatory cytokine production, and scavenge free radicals. These compounds may modulate cellular signaling pathways involved in inflammation and oxidative stress, though the exact molecular targets vary depending on the specific bioactive constituent and cell type.","oneSentence":"Lemongrass oil contains volatile compounds (citral, geraniol, limonene) that exhibit antimicrobial, anti-inflammatory, and antioxidant properties through multiple cellular pathways.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T04:13:48.789Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Traditional use for digestive complaints and inflammation"},{"name":"Antimicrobial applications in traditional medicine"},{"name":"Antioxidant support (marketed/traditional use)"}]},"trialDetails":[{"nctId":"NCT07237061","phase":"NA","title":"Patient-preferred Aromatherapy Versus Placebo For Reducing Preoperative Anxiety In Patients Undergoing Eye Surgery","status":"COMPLETED","sponsor":"National University Hospital, Singapore","startDate":"2023-03-01","conditions":"Cataract, Surgery, Vitrectomy","enrollment":64},{"nctId":"NCT07113080","phase":"PHASE4","title":"Assessing the Efficacy of Lemongrass and Lavender Aromatherapy in Reducing Dental Anxiety and Pain Associated With Local Anesthetic Injections in Pediatric Dental Patients","status":"RECRUITING","sponsor":"Hiba Ahmed Eltayeb","startDate":"2025-02-21","conditions":"Dental Fear and Anxiety","enrollment":48},{"nctId":"NCT06146712","phase":"NA","title":"A Single-Group Study to Examine the Efficacy of a Melatonin Lotion With Magnesium to Improve Sleep Quality and Quantity","status":"COMPLETED","sponsor":"Asutra","startDate":"2023-08-07","conditions":"Sleep","enrollment":35},{"nctId":"NCT05599594","phase":"NA","title":"Premenstrual Symptoms and Aromatherapy","status":"UNKNOWN","sponsor":"KTO Karatay University","startDate":"2023-12-15","conditions":"Premenstrual Syndrome, Aromatherapy","enrollment":120},{"nctId":"NCT06068777","phase":"NA","title":"The Impact of Aromatherapy on Alleviating Dental Anxiety in Children","status":"COMPLETED","sponsor":"Suez Canal University","startDate":"2022-03-23","conditions":"Pain Syndrome","enrollment":45},{"nctId":"NCT05502627","phase":"","title":"To Study the Healing Effect of 0.25% Lemongrass Oil Mouthwash on Chronic Periodontitis Patients.","status":"COMPLETED","sponsor":"Postgraduate Medical Institute, Lahore","startDate":"2021-04-01","conditions":"Chronic Periodontitis","enrollment":30},{"nctId":"NCT05202366","phase":"","title":"An Open-label Study Evaluating the Effectiveness of CGB-400 Topical Gel for Fungal Infection","status":"UNKNOWN","sponsor":"CAGE Bio Inc.","startDate":"2022-02-08","conditions":"Fungal Infection, Onychomycosis, Tinea Unguium","enrollment":15},{"nctId":"NCT05241509","phase":"PHASE4","title":"Cymbopogon Citratus Gel as Local Drug Delivery Agent in Reducing Matrix Metalloproteinase-8 Levels Intra-crevicularly in the Treatment of Stage II Periodontitis","status":"COMPLETED","sponsor":"Souzy Kamal","startDate":"2019-07-06","conditions":"Periodontitis Chronic Generalized Moderate","enrollment":40},{"nctId":"NCT05168098","phase":"NA","title":"Impact of the Olfactory Stimulation on the People With Mild Dementia Via the Horticultural Therapy","status":"COMPLETED","sponsor":"National Taiwan Normal University","startDate":"2019-10-01","conditions":"Dementia","enrollment":28},{"nctId":"NCT04963829","phase":"PHASE1","title":"Unripe Banana Peel Powder and Lemongrass Oil in Chronic Ulcer","status":"COMPLETED","sponsor":"Universidade do Vale do Sapucai","startDate":"2018-02-02","conditions":"Chronic Ulcer, Healing Ulcer","enrollment":25},{"nctId":"NCT04605289","phase":"PHASE1, PHASE2","title":"Levels of Matrix Metalloproteinase-8 After Intrapocket Treatment in Moderate Periodontitis Patients.","status":"COMPLETED","sponsor":"Alexandria University","startDate":"2020-01-13","conditions":"Periodontitis","enrollment":40}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":175,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Lemongrass Oil","genericName":"Lemongrass Oil","companyName":"Suez Canal University","companyId":"suez-canal-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Lemongrass oil contains volatile compounds (citral, geraniol, limonene) that exhibit antimicrobial, anti-inflammatory, and antioxidant properties through multiple cellular pathways. Used for Traditional use for digestive complaints and inflammation, Antimicrobial applications in traditional medicine.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}