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Kybella Flanks
Kybella (deoxycholic acid) destroys fat cells through a naturally occurring bile acid that disrupts cell membranes, leading to permanent reduction of submental fat.
Kybella (deoxycholic acid) destroys fat cells through a naturally occurring bile acid that disrupts cell membranes, leading to permanent reduction of submental fat. Used for Reduction of submental fat (double chin) in adults.
At a glance
| Generic name | Kybella Flanks |
|---|---|
| Sponsor | Beer, Kenneth R., M.D., PA |
| Drug class | Lipid-dissolving agent |
| Target | Adipocyte cell membrane |
| Modality | Small molecule |
| Therapeutic area | Dermatology / Aesthetics |
| Phase | FDA-approved |
Mechanism of action
Deoxycholic acid is a naturally occurring bile acid that, when injected into subcutaneous fat, causes adipocyte lysis and permanent destruction of fat cells. The body then metabolizes and eliminates the destroyed fat cells through normal physiological processes. This results in a permanent reduction of localized fat deposits in the treated area.
Approved indications
- Reduction of submental fat (double chin) in adults
Common side effects
- Swelling and bruising at injection site
- Pain or tenderness
- Redness and warmth
- Numbness or altered sensation in lower face/neck
- Difficulty swallowing
- Nerve injury (marginal mandibular nerve)
Key clinical trials
- Evaluating the Efficacy and Safety of Embella (Deoxycholic Acid, Produced by Espad Pharmed Co.) for the Treatment of Flank Fat (NA)
- Kybella for the Treatment of Flank Fat (FF) (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Kybella Flanks CI brief — competitive landscape report
- Kybella Flanks updates RSS · CI watch RSS
- Beer, Kenneth R., M.D., PA portfolio CI