{"id":"kybella-flanks","safety":{"commonSideEffects":[{"rate":"~80","effect":"Swelling and bruising at injection site"},{"rate":"~70","effect":"Pain or tenderness"},{"rate":"~60","effect":"Redness and warmth"},{"rate":"~40","effect":"Numbness or altered sensation in lower face/neck"},{"rate":"~10","effect":"Difficulty swallowing"},{"rate":"<1","effect":"Nerve injury (marginal mandibular nerve)"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Deoxycholic acid is a naturally occurring bile acid that, when injected into subcutaneous fat, causes adipocyte lysis and permanent destruction of fat cells. The body then metabolizes and eliminates the destroyed fat cells through normal physiological processes. This results in a permanent reduction of localized fat deposits in the treated area.","oneSentence":"Kybella (deoxycholic acid) destroys fat cells through a naturally occurring bile acid that disrupts cell membranes, leading to permanent reduction of submental fat.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:51:15.764Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Reduction of submental fat (double chin) in adults"}]},"trialDetails":[{"nctId":"NCT07004010","phase":"NA","title":"Evaluating the Efficacy and Safety of Embella (Deoxycholic Acid, Produced by Espad Pharmed Co.) for the Treatment of Flank Fat","status":"COMPLETED","sponsor":"Espad Pharmed","startDate":"2024-08-01","conditions":"Flank Fat","enrollment":30},{"nctId":"NCT04841551","phase":"PHASE4","title":"Kybella for the Treatment of Flank Fat (FF)","status":"COMPLETED","sponsor":"Beer, Kenneth R., M.D., PA","startDate":"2021-07-22","conditions":"Adiposity","enrollment":10}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Kybella Flanks","genericName":"Kybella Flanks","companyName":"Beer, Kenneth R., M.D., PA","companyId":"beer-kenneth-r-m-d-pa","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Kybella (deoxycholic acid) destroys fat cells through a naturally occurring bile acid that disrupts cell membranes, leading to permanent reduction of submental fat. Used for Reduction of submental fat (double chin) in adults.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}