Last reviewed · How we verify

Ketorolac Oral Tablet [Toradol]

Montefiore Medical Center · Phase 3 active Small molecule

Ketorolac inhibits cyclooxygenase (COX) enzymes to reduce prostaglandin synthesis, thereby decreasing inflammation and pain.

Ketorolac inhibits cyclooxygenase (COX) enzymes to reduce prostaglandin synthesis, thereby decreasing inflammation and pain. Used for Moderate to severe acute pain (short-term use), Postoperative pain.

At a glance

Generic nameKetorolac Oral Tablet [Toradol]
Also known asToradol
SponsorMontefiore Medical Center
Drug classNonsteroidal anti-inflammatory drug (NSAID)
TargetCOX-1 and COX-2
ModalitySmall molecule
Therapeutic areaPain Management
PhasePhase 3

Mechanism of action

As a nonsteroidal anti-inflammatory drug (NSAID), ketorolac blocks both COX-1 and COX-2 enzymes, which are responsible for producing prostaglandins that mediate inflammation, pain, and fever. By reducing prostaglandin levels, ketorolac provides rapid analgesic and anti-inflammatory effects. It is typically used for short-term management of moderate to severe acute pain.

Approved indications

Common side effects

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape: