{"id":"ketorolac-oral-tablet-toradol","safety":{"commonSideEffects":[{"rate":"10-15","effect":"Gastrointestinal upset (nausea, dyspepsia)"},{"rate":"5-10","effect":"Headache"},{"rate":"5-10","effect":"Dizziness"},{"rate":null,"effect":"Renal impairment"},{"rate":"1-2","effect":"Gastrointestinal bleeding"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"As a nonsteroidal anti-inflammatory drug (NSAID), ketorolac blocks both COX-1 and COX-2 enzymes, which are responsible for producing prostaglandins that mediate inflammation, pain, and fever. By reducing prostaglandin levels, ketorolac provides rapid analgesic and anti-inflammatory effects. It is typically used for short-term management of moderate to severe acute pain.","oneSentence":"Ketorolac inhibits cyclooxygenase (COX) enzymes to reduce prostaglandin synthesis, thereby decreasing inflammation and pain.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:49:08.024Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Moderate to severe acute pain (short-term use)"},{"name":"Postoperative pain"}]},"trialDetails":[],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":4,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Toradol"],"phase":"phase_3","status":"active","brandName":"Ketorolac Oral Tablet [Toradol]","genericName":"Ketorolac Oral Tablet [Toradol]","companyName":"Montefiore Medical Center","companyId":"montefiore-medical-center","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ketorolac inhibits cyclooxygenase (COX) enzymes to reduce prostaglandin synthesis, thereby decreasing inflammation and pain. Used for Moderate to severe acute pain (short-term use), Postoperative pain.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":false,"score":3}}