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iso-amyl- 2-cyanoacrylate.
Iso-amyl-2-cyanoacrylate is a tissue adhesive that polymerizes rapidly upon contact with moisture to form a strong bond between tissue surfaces.
Iso-amyl-2-cyanoacrylate is a tissue adhesive that polymerizes rapidly upon contact with moisture to form a strong bond between tissue surfaces. Used for Surgical hemostasis and wound closure, Tissue adhesion in surgical applications.
At a glance
| Generic name | iso-amyl- 2-cyanoacrylate. |
|---|---|
| Sponsor | Ain Shams University |
| Drug class | Tissue adhesive / Hemostatic agent |
| Modality | Small molecule |
| Therapeutic area | Surgery / Wound Care |
| Phase | Phase 3 |
Mechanism of action
This cyanoacrylate-based adhesive undergoes anionic polymerization when exposed to water or biological fluids, creating a plastic polymer that mechanically bonds tissues together. It is used as a surgical hemostatic and adhesive agent to seal wounds, control bleeding, and approximate tissue surfaces without traditional sutures or staples.
Approved indications
- Surgical hemostasis and wound closure
- Tissue adhesion in surgical applications
Common side effects
- Tissue irritation or inflammation
- Allergic reaction
- Delayed wound healing
Key clinical trials
- Hysteroscopic Tubal Occlusion Using Amacrylate With or Without Lipidol in Patients With Hydrosalpinx Prior to IVF (PHASE3)
- Hysteroscopic Tubal Occlusion Using Iso-Amyl 2-Cyano Acrylate (Amcrylate) in Patients With Hydrosalpinx (PHASE1, PHASE2)
- Hysteroscopic Tubal Occlusion With the Use of Iso Amyl-2-cyanoacrylate (PHASE1)
- N-butyl-2-cyanoacrylate, Iso-amyl-2-cyanoacrylate and Hypertonic Glucose With 72% Chromated Glycerin in Gastric Varices (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- iso-amyl- 2-cyanoacrylate. CI brief — competitive landscape report
- iso-amyl- 2-cyanoacrylate. updates RSS · CI watch RSS
- Ain Shams University portfolio CI