{"id":"iso-amyl-2-cyanoacrylate","safety":{"commonSideEffects":[{"rate":null,"effect":"Tissue irritation or inflammation"},{"rate":null,"effect":"Allergic reaction"},{"rate":null,"effect":"Delayed wound healing"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"anthropic-haiku","explanation":"This cyanoacrylate-based adhesive undergoes anionic polymerization when exposed to water or biological fluids, creating a plastic polymer that mechanically bonds tissues together. It is used as a surgical hemostatic and adhesive agent to seal wounds, control bleeding, and approximate tissue surfaces without traditional sutures or staples.","oneSentence":"Iso-amyl-2-cyanoacrylate is a tissue adhesive that polymerizes rapidly upon contact with moisture to form a strong bond between tissue surfaces.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T01:17:18.313Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Surgical hemostasis and wound closure"},{"name":"Tissue adhesion in surgical applications"}]},"trialDetails":[{"nctId":"NCT06130072","phase":"PHASE3","title":"Hysteroscopic Tubal Occlusion Using Amacrylate With or Without Lipidol in Patients With Hydrosalpinx Prior to IVF","status":"UNKNOWN","sponsor":"Ain Shams University","startDate":"2023-11-10","conditions":"Effectiveness of Isoamyl-2-cyanoacrylate With and Without Ethiodized Oil in Occluding Hydrosalpinx Prior to IVF","enrollment":45},{"nctId":"NCT02977234","phase":"PHASE1, PHASE2","title":"Hysteroscopic Tubal Occlusion Using Iso-Amyl 2-Cyano Acrylate (Amcrylate) in Patients With Hydrosalpinx","status":"UNKNOWN","sponsor":"Ain Shams University","startDate":"2016-10","conditions":"Hydrosalpinx, Infertility, Female","enrollment":40},{"nctId":"NCT02698644","phase":"PHASE1","title":"Hysteroscopic Tubal Occlusion With the Use of Iso Amyl-2-cyanoacrylate","status":"UNKNOWN","sponsor":"Ain Shams University","startDate":"2016-01","conditions":"Fallopian Tube Occlusion","enrollment":25},{"nctId":"NCT02330731","phase":"NA","title":"N-butyl-2-cyanoacrylate, Iso-amyl-2-cyanoacrylate and Hypertonic Glucose With 72% Chromated Glycerin in Gastric Varices","status":"COMPLETED","sponsor":"Ain Shams University","startDate":"2012-01","conditions":"Gastric Varices","enrollment":90}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":6,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"iso-amyl- 2-cyanoacrylate.","genericName":"iso-amyl- 2-cyanoacrylate.","companyName":"Ain Shams University","companyId":"ain-shams-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Iso-amyl-2-cyanoacrylate is a tissue adhesive that polymerizes rapidly upon contact with moisture to form a strong bond between tissue surfaces. Used for Surgical hemostasis and wound closure, Tissue adhesion in surgical applications.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}