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Iron Sucrose Supplement
Iron sucrose provides bioavailable iron that is absorbed and incorporated into hemoglobin and other iron-dependent proteins to treat iron deficiency.
Iron sucrose provides bioavailable iron that is absorbed and incorporated into hemoglobin and other iron-dependent proteins to treat iron deficiency. Used for Iron deficiency anemia in patients with chronic kidney disease, Iron deficiency anemia in patients on hemodialysis or peritoneal dialysis, Iron deficiency anemia in non-dialysis chronic kidney disease patients.
At a glance
| Generic name | Iron Sucrose Supplement |
|---|---|
| Sponsor | Papageorgiou General Hospital |
| Drug class | Iron supplement |
| Modality | Small molecule |
| Therapeutic area | Hematology |
| Phase | FDA-approved |
Mechanism of action
Iron sucrose is a stable complex of iron (III) hydroxide with sucrose that delivers iron for erythropoiesis and cellular function. After administration, the iron is released and transported via transferrin to bone marrow for incorporation into hemoglobin synthesis, and to tissues for myoglobin and iron-dependent enzyme production. This replenishes depleted iron stores and corrects iron deficiency anemia.
Approved indications
- Iron deficiency anemia in patients with chronic kidney disease
- Iron deficiency anemia in patients on hemodialysis or peritoneal dialysis
- Iron deficiency anemia in non-dialysis chronic kidney disease patients
Common side effects
- Hypotension
- Nausea
- Vomiting
- Abdominal pain
- Headache
- Diarrhea
- Injection site reactions
Key clinical trials
- Iron and Immune Response to Vaccine (IRONMUM) (NA)
- Pilot Study Evaluating the Advantages of Sucrosomial® Iron Post-operative Supplementation vs Standard of Care After Cardiac Surgery (EARLY_PHASE1)
- Exercise and Galactooligosaccharide Supplementation on Inflammation and Iron Absorption (FexerGOS) (NA)
- Effect of Intravenously Iron Infusion on the Prevention and Treatment of Anemia in Ovarian Cancer (PHASE3)
- Iron Supplementation for Geriatric Hip Fractures (PHASE4)
- The TARGET-EFT Randomized Clinical Trial (NA)
- Efficacy and Safety of Venofer (Iron Sucrose Injection USP) in Patients Receiving Peritoneal Dialysis (PHASE3)
- A Novel Nano-iron Supplement to Safely Combat Iron Deficiency and Anaemia in Young Children: a Doubleblind Randomised Controlled Trial (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Iron Sucrose Supplement CI brief — competitive landscape report
- Iron Sucrose Supplement updates RSS · CI watch RSS
- Papageorgiou General Hospital portfolio CI