{"id":"iron-sucrose-supplement","safety":{"commonSideEffects":[{"rate":null,"effect":"Hypotension"},{"rate":null,"effect":"Nausea"},{"rate":null,"effect":"Vomiting"},{"rate":null,"effect":"Abdominal pain"},{"rate":null,"effect":"Headache"},{"rate":null,"effect":"Diarrhea"},{"rate":null,"effect":"Injection site reactions"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Iron sucrose is a stable complex of iron (III) hydroxide with sucrose that delivers iron for erythropoiesis and cellular function. After administration, the iron is released and transported via transferrin to bone marrow for incorporation into hemoglobin synthesis, and to tissues for myoglobin and iron-dependent enzyme production. This replenishes depleted iron stores and corrects iron deficiency anemia.","oneSentence":"Iron sucrose provides bioavailable iron that is absorbed and incorporated into hemoglobin and other iron-dependent proteins to treat iron deficiency.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:50:16.793Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Iron deficiency anemia in patients with chronic kidney disease"},{"name":"Iron deficiency anemia in patients on hemodialysis or peritoneal dialysis"},{"name":"Iron deficiency anemia in non-dialysis chronic kidney disease patients"}]},"trialDetails":[{"nctId":"NCT05385042","phase":"NA","title":"Iron and Immune Response to Vaccine (IRONMUM)","status":"COMPLETED","sponsor":"University of Oxford","startDate":"2022-06-18","conditions":"Pregnancy Related","enrollment":171},{"nctId":"NCT06970925","phase":"EARLY_PHASE1","title":"Pilot Study Evaluating the Advantages of Sucrosomial® Iron Post-operative Supplementation vs Standard of Care After Cardiac Surgery","status":"RECRUITING","sponsor":"Englewood Hospital and Medical Center","startDate":"2025-06-30","conditions":"Cardiac Surgery","enrollment":40},{"nctId":"NCT06038656","phase":"NA","title":"Exercise and Galactooligosaccharide Supplementation on Inflammation and Iron Absorption (FexerGOS)","status":"COMPLETED","sponsor":"North-West University, South Africa","startDate":"2024-03-01","conditions":"Resistance Exercise","enrollment":22},{"nctId":"NCT06248749","phase":"PHASE3","title":"Effect of Intravenously Iron Infusion on the Prevention and Treatment of Anemia in Ovarian Cancer","status":"NOT_YET_RECRUITING","sponsor":"University of Saskatchewan","startDate":"2024-02-29","conditions":"Anaemia in Ovarian Carcinoma","enrollment":200},{"nctId":"NCT05489952","phase":"PHASE4","title":"Iron Supplementation for Geriatric Hip Fractures","status":"UNKNOWN","sponsor":"He Qifei","startDate":"2022-09-15","conditions":"Hip Fractures, Fragility Fracture, Osteoporotic Fractures","enrollment":444},{"nctId":"NCT04291690","phase":"NA","title":"The TARGET-EFT Randomized Clinical Trial","status":"COMPLETED","sponsor":"Jonathan Afilalo","startDate":"2020-03-05","conditions":"Frailty, Cardiovascular Diseases in Old Age, Geriatric Cardiology","enrollment":144},{"nctId":"NCT00236938","phase":"PHASE3","title":"Efficacy and Safety of Venofer (Iron Sucrose Injection USP) in Patients Receiving Peritoneal Dialysis","status":"COMPLETED","sponsor":"American Regent, Inc.","startDate":"2002-07","conditions":"Anemia","enrollment":121},{"nctId":"NCT02941081","phase":"PHASE2","title":"A Novel Nano-iron Supplement to Safely Combat Iron Deficiency and Anaemia in Young Children: a Doubleblind Randomised Controlled Trial","status":"COMPLETED","sponsor":"London School of Hygiene and Tropical Medicine","startDate":"2018-01-08","conditions":"Iron Deficiency, Anaemia in Children","enrollment":645},{"nctId":"NCT03771092","phase":"NA","title":"Comparing the Efficacy of Different Iron Formulations: Sucrosomal Ferric Pyrophosphate, SunActive®Fe and Intravenous Ferric Gluconate","status":"COMPLETED","sponsor":"University of Palermo","startDate":"2015-11-02","conditions":"Iron Deficiency Anemia","enrollment":148},{"nctId":"NCT02787824","phase":"PHASE4","title":"Periodic Versus Continuous IV Iron Supplementation in HD Patients","status":"COMPLETED","sponsor":"Papageorgiou General Hospital","startDate":"2016-05","conditions":"Anemia of Chronic Kidney Disease","enrollment":27}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Iron Sucrose Supplement","genericName":"Iron Sucrose Supplement","companyName":"Papageorgiou General Hospital","companyId":"papageorgiou-general-hospital","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Iron sucrose provides bioavailable iron that is absorbed and incorporated into hemoglobin and other iron-dependent proteins to treat iron deficiency. Used for Iron deficiency anemia in patients with chronic kidney disease, Iron deficiency anemia in patients on hemodialysis or peritoneal dialysis, Iron deficiency anemia in non-dialysis chronic kidney disease patients.","enrichmentLevel":3,"visitCount":2,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}