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IP Saline bolus and infusion
IP saline bolus and infusion delivers isotonic sodium chloride solution intravenously to restore fluid and electrolyte balance.
IP saline bolus and infusion delivers isotonic sodium chloride solution intravenously to restore fluid and electrolyte balance. Used for Hypovolemia and dehydration, Fluid resuscitation in acute care and emergency settings, Maintenance fluid therapy.
At a glance
| Generic name | IP Saline bolus and infusion |
|---|---|
| Also known as | Lidocaine |
| Sponsor | University of Auckland, New Zealand |
| Drug class | Crystalloid fluid / Electrolyte replacement |
| Modality | Small molecule |
| Therapeutic area | Critical Care / Emergency Medicine / General Supportive Care |
| Phase | FDA-approved |
Mechanism of action
Intravenous saline (0.9% sodium chloride) is an isotonic crystalloid fluid that replaces intravascular volume and maintains electrolyte homeostasis. It is used for fluid resuscitation, maintenance therapy, and as a vehicle for drug delivery in acute care settings. The solution equilibrates across fluid compartments to restore circulating volume and correct dehydration or hypovolemia.
Approved indications
- Hypovolemia and dehydration
- Fluid resuscitation in acute care and emergency settings
- Maintenance fluid therapy
- Vehicle for intravenous drug administration
Common side effects
- Hyperchloremic acidosis
- Fluid overload / pulmonary edema
- Hypernatremia
- Phlebitis at infusion site
Key clinical trials
- Antigen Specific Adoptive T Cell Therapy for Adenovirus Infection After Hematopoietic Stem Cell Transplantation (EARLY_PHASE1)
- A Study to Investigate ONCOS-102 in Combination With Durvalumab in Subjects With Advanced Peritoneal Malignancies (PHASE1, PHASE2)
- Intravenous and Intraperitoneal Lignocaine for Perioperative Analgesia in Laparoscopic Colon Resections (PHASE4)
- Efficacy of Intraperitoneal Versus Intravenous Lidocaine for Postcesarean Pain Relief (PHASE2, PHASE3)
- The Effect of Intravenous Lidocaine and Intraperitoneal Lidocaine Irrigation on Pain After Laparoscopic Cholecystectomy (PHASE4)
- Effect of Intraperitoneal and Intravenous Lignocaine on Pain Relief Following Laparoscopic Cholecystectomy (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- IP Saline bolus and infusion CI brief — competitive landscape report
- IP Saline bolus and infusion updates RSS · CI watch RSS
- University of Auckland, New Zealand portfolio CI