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Iontophoresis with acetylcholine delivery
Acetylcholine delivery via iontophoresis stimulates nicotinic acetylcholine receptors.
Acetylcholine delivery via iontophoresis stimulates nicotinic acetylcholine receptors. Used for Tourette syndrome, Dystonia.
At a glance
| Generic name | Iontophoresis with acetylcholine delivery |
|---|---|
| Sponsor | Assistance Publique - Hôpitaux de Paris |
| Drug class | Cholinergic agent |
| Target | Nicotinic acetylcholine receptor |
| Modality | Small molecule |
| Therapeutic area | Neurology |
| Phase | Phase 2 |
Mechanism of action
Iontophoresis is a non-invasive method that uses a low-intensity electric current to drive acetylcholine across the skin, where it can interact with nicotinic acetylcholine receptors. This can potentially have therapeutic effects in various conditions.
Approved indications
- Tourette syndrome
- Dystonia
Common side effects
- Skin irritation
- Muscle weakness
- Headache
Key clinical trials
- The Effects of Anthracycline-based Chemotherapy on Peripheral Vascular Function
- Microcirculatory Impairment in Patients With Leprosy (NA)
- Endothelial Dysfunction and Diabetes
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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