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Intercostal nerve block

George Washington University · Phase 3 active Small molecule

An intercostal nerve block is a regional anesthesia technique that delivers local anesthetic to the intercostal nerves to block pain sensation in the chest wall.

An intercostal nerve block is a regional anesthesia technique that delivers local anesthetic to the intercostal nerves to block pain sensation in the chest wall. Used for Post-operative pain management following thoracic surgery, Rib fracture pain management, Acute chest wall pain.

At a glance

Generic nameIntercostal nerve block
SponsorGeorge Washington University
ModalitySmall molecule
Therapeutic areaAnesthesia/Pain Management
PhasePhase 3

Mechanism of action

This procedure involves injecting local anesthetic around the intercostal nerves that run along the ribs, temporarily interrupting pain signals from the chest wall and rib cage. It is used to provide analgesia for thoracic and upper abdominal surgical procedures, rib fractures, and post-operative pain management. The block can be administered as a single injection or continuous infusion via catheter.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results