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Insulin treatment for hyperglycemia
Insulin treatment for hyperglycemia is a Insulin Small molecule drug developed by University of Michigan. It is currently FDA-approved for Type 1 diabetes mellitus, Type 2 diabetes mellitus (when oral agents are insufficient), Hyperglycemia in hospitalized patients.
Insulin replaces or supplements the body's own insulin to lower blood glucose by promoting glucose uptake into cells and storage as glycogen.
Insulin replaces or supplements the body's own insulin to lower blood glucose by promoting glucose uptake into cells and storage as glycogen. Used for Type 1 diabetes mellitus, Type 2 diabetes mellitus (when oral agents are insufficient), Hyperglycemia in hospitalized patients.
At a glance
| Generic name | Insulin treatment for hyperglycemia |
|---|---|
| Sponsor | University of Michigan |
| Drug class | Insulin |
| Target | Insulin receptor |
| Modality | Small molecule |
| Therapeutic area | Endocrinology / Diabetes |
| Phase | FDA-approved |
Mechanism of action
Insulin is a hormone that binds to insulin receptors on muscle, fat, and liver cells, facilitating glucose transport from the bloodstream into these tissues for energy use or storage. This reduces circulating blood glucose levels in hyperglycemic patients. Insulin also suppresses hepatic glucose production and promotes anabolic processes.
Approved indications
- Type 1 diabetes mellitus
- Type 2 diabetes mellitus (when oral agents are insufficient)
- Hyperglycemia in hospitalized patients
Common side effects
- Hypoglycemia
- Weight gain
- Injection site reactions
- Lipodystrophy
Key clinical trials
- Effects of Diabetic Educational Intervention and Dietary Supplements on Blood Glucose, Lipid Profile Levels, Body Mass Index, and Pain Management Among Adult Individuals With Painful Diabetic Peripheral Neuropathy. (NA)
- Isoleucine Addition Treatment Effects in a Controlled Diet Study (NA)
- Oral Anti Diabetic Agents in the Hospital (PHASE4)
- Impact of Insulin Deprivation and Hyperglycemia on Plasma Protein Synthesis in People With Type 1 Diabetes Mellitus (NA)
- Prevention and Treatment of Common Hyperglycemia in Surgery Pilot (PHASE4)
- Alpelisib/iNOS Inhibitor/Nab-paclitaxel in Patients With HER2 Negative Metaplastic Breast Cancer (MpBC) (PHASE2)
- Role of Alpha-to-beta Cell Communication to Adapt Insulin Secretion to Insulin Resistance. (PHASE1)
- Time in rANge vs. Time in nOrmal Glycemia for Better Glycemic Control (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Insulin treatment for hyperglycemia CI brief — competitive landscape report
- Insulin treatment for hyperglycemia updates RSS · CI watch RSS
- University of Michigan portfolio CI
Frequently asked questions about Insulin treatment for hyperglycemia
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Related
- Drug class: All Insulin drugs
- Target: All drugs targeting Insulin receptor
- Manufacturer: University of Michigan — full pipeline
- Therapeutic area: All drugs in Endocrinology / Diabetes
- Indication: Drugs for Type 1 diabetes mellitus
- Indication: Drugs for Type 2 diabetes mellitus (when oral agents are insufficient)
- Indication: Drugs for Hyperglycemia in hospitalized patients
- Compare: Insulin treatment for hyperglycemia vs similar drugs
- Pricing: Insulin treatment for hyperglycemia cost, discount & access