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hydrolyzed guar gum
hydrolyzed guar gum is a Small molecule drug developed by IRCCS San Raffaele Roma. It is currently in Phase 2 development. Also known as: PHGG.
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Baseline phase 2 → approval rate
+15.3pp
Industry-wide phase 2 drugs reach approval ~15.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
| Regulator | Country | Likely year | Lag vs FDA |
|---|---|---|---|
| FDA | US | 2031–2034 | — |
| EMA | EU | 2032–2035 | +0.7 yr |
| MHRA | GB | 2032–2035 | +0.7 yr |
| Health Canada | CA | 2032–2036 | +0.9 yr |
| TGA | AU | 2032–2036 | +1.2 yr |
| PMDA | JP | 2032–2036 | +1.5 yr |
| NMPA | CN | 2033–2037 | +2.3 yr |
| MFDS | KR | 2032–2036 | +1.4 yr |
| CDSCO | IN | 2032–2037 | +1.8 yr |
| ANVISA | BR | 2033–2037 | +2.3 yr |
Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).
Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.
At a glance
| Generic name | hydrolyzed guar gum |
|---|---|
| Also known as | PHGG |
| Sponsor | IRCCS San Raffaele Roma |
| Modality | Small molecule |
| Phase | Phase 2 |
Approved indications
Common side effects
Key clinical trials
- Impact of Different Dietary Fibers in Gastric Emptying Time and Intestinal Transit of Healthy Volunteers (NA)
- Probiotic and Prebiotic Use in Early Postoperative Period of Sleeve Gastrectomy (NA)
- Evaluation of Changes in Bowel Movement Frequency Following the Consumption of PHGG in Adults with Constipation (NA)
- Study to Evaluate the Tolerance and Safety of a Peptide-based Enteral Formula with Partially Hydrolyzed Guar Gum (PHGG) (NA)
- Evaluation of Changes in Bowel Movement Frequency Following the Consumption of PHGG Compared to Placebo (NA)
- Treatment of Chronic Constipation in Parkinson's Disease (PHASE2)
- Effects of a Combination of Polyphenol-rich Extracts, Prebiotics, and Hydrolyzed Fiber on the Quality of Life of Patients With Irritable Bowel Syndrome (IBS) (NA)
- Improving the Iron Status of Athletes With Pre-, Pro- and Synbiotics (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- hydrolyzed guar gum CI brief — competitive landscape report
- hydrolyzed guar gum updates RSS · CI watch RSS
- IRCCS San Raffaele Roma portfolio CI
Frequently asked questions about hydrolyzed guar gum
What is hydrolyzed guar gum?
Who makes hydrolyzed guar gum?
Is hydrolyzed guar gum also known as anything else?
What development phase is hydrolyzed guar gum in?
Related
- Manufacturer: IRCCS San Raffaele Roma — full pipeline
- Also known as: PHGG
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing