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Hand antisepsis by scrub
Hand antisepsis by scrub mechanically removes and chemically inactivates microorganisms from the skin surface through friction and antimicrobial agents.
Hand antisepsis by scrub mechanically removes and chemically inactivates microorganisms from the skin surface through friction and antimicrobial agents. Used for Preoperative hand antisepsis for surgical personnel, Clinical hand hygiene in healthcare settings.
At a glance
| Generic name | Hand antisepsis by scrub |
|---|---|
| Also known as | Propanolol |
| Sponsor | Universidad Complutense de Madrid |
| Modality | Small molecule |
| Therapeutic area | Infection Prevention / Surgical Prophylaxis |
| Phase | FDA-approved |
Mechanism of action
This is a procedural antiseptic intervention rather than a pharmaceutical drug. It combines mechanical action (scrubbing) with antimicrobial agents (typically alcohols, chlorhexidine, or iodine-based compounds) to reduce the microbial load on hands before surgical or clinical procedures. The scrubbing action physically dislodges bacteria and viruses while the chemical agents denature microbial cell membranes and proteins.
Approved indications
- Preoperative hand antisepsis for surgical personnel
- Clinical hand hygiene in healthcare settings
Common side effects
- Skin irritation or dermatitis
- Dryness or scaling
- Allergic contact dermatitis
Key clinical trials
- Pre-surgical Antisepsis of Hands After Washing With Triclosan 0.5% Compared to Propan-1-ol 60% (PHASE4)
- Pre-surgical Antisepsis Using an Alcoholic Solution of Chlorhexidine Digluconate and Potassium Sorbate (PHASE4)
- Surgical Hand Antisepsis With Propan-ol-1 60% Per Rubbing and Scrubbing (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Hand antisepsis by scrub CI brief — competitive landscape report
- Hand antisepsis by scrub updates RSS · CI watch RSS
- Universidad Complutense de Madrid portfolio CI