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Glycolic Acid 70%
Glycolic acid is an alpha-hydroxy acid (AHA) that exfoliates the skin by dissolving the bonds between dead skin cells, promoting cell turnover and revealing fresher skin underneath.
Glycolic acid is an alpha-hydroxy acid (AHA) that exfoliates the skin by dissolving the bonds between dead skin cells, promoting cell turnover and revealing fresher skin underneath. Used for Acne vulgaris, Photoaging and fine lines, Hyperpigmentation and melasma.
At a glance
| Generic name | Glycolic Acid 70% |
|---|---|
| Also known as | Peeling agent |
| Sponsor | Combined Military Hospital Abbottabad |
| Drug class | Alpha-hydroxy acid (AHA) exfoliant |
| Modality | Small molecule |
| Therapeutic area | Dermatology |
| Phase | FDA-approved |
Mechanism of action
Glycolic acid penetrates the stratum corneum and breaks down desmosomes (intercellular adhesion structures) through hydrolysis, accelerating the natural desquamation process. This chemical exfoliation stimulates collagen and elastin production in the dermis, improving skin texture, reducing fine lines, and treating acne and hyperpigmentation. At 70% concentration, it is a professional-strength formulation typically used in clinical peels.
Approved indications
- Acne vulgaris
- Photoaging and fine lines
- Hyperpigmentation and melasma
- Keratosis pilaris
- Chemical peeling agent
Common side effects
- Erythema (redness)
- Irritation and burning sensation
- Peeling and flaking
- Photosensitivity
- Post-inflammatory hyperpigmentation
Key clinical trials
- Comparison of Chemical Peeling Agent With Transamine for Treatment of Melasma (PHASE1)
- New Score for Pseudo- Acanthosis Nigricans (NA)
- Assessment of the Cosmetic Benefit of a Skin Cream in Healthy Females With Mild to Advanced Photo-damaged Facial Skin Who Have Undergone a Glycolic Acid Facial Peel Procedure (NA)
- Evaluation of the Cosmetic Benefit of a Skin Cream in Healthy Females With Mild to Advanced Photo-damaged Facial Skin Who Have Undergone a Glycolic Acid Facial Peel Procedure (NA)
- BiOSS LIM C vs 2nd Generation DES in Non-LM Bifurcations (PHASE4)
- Modified Jessner's Solution With Trichloroacetic Acid Versus Glycolic Acid With Trichloroacetic Acid (PHASE4)
- The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Photoaging (PHASE2)
- The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Acne Scars (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Glycolic Acid 70% CI brief — competitive landscape report
- Glycolic Acid 70% updates RSS · CI watch RSS
- Combined Military Hospital Abbottabad portfolio CI