{"id":"glycolic-acid-70","safety":{"commonSideEffects":[{"rate":null,"effect":"Erythema (redness)"},{"rate":null,"effect":"Irritation and burning sensation"},{"rate":null,"effect":"Peeling and flaking"},{"rate":null,"effect":"Photosensitivity"},{"rate":null,"effect":"Post-inflammatory hyperpigmentation"}]},"_chembl":null,"_dailymed":{"setId":"29e8bc89-f58c-c177-e063-6394a90af7cd","title":"MELAO GLYCOLIC ACID PEEL 70% (ROSMARINUS OFFICINALIS (ROSEMARY) LEAF EXTRACT 0.3% CENTELLA ASIATICA EXTRACT 0.15%) LIQUID [GUANGZHOU YILONG COSMETICS CO., LTD]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Glycolic acid penetrates the stratum corneum and breaks down desmosomes (intercellular adhesion structures) through hydrolysis, accelerating the natural desquamation process. This chemical exfoliation stimulates collagen and elastin production in the dermis, improving skin texture, reducing fine lines, and treating acne and hyperpigmentation. At 70% concentration, it is a professional-strength formulation typically used in clinical peels.","oneSentence":"Glycolic acid is an alpha-hydroxy acid (AHA) that exfoliates the skin by dissolving the bonds between dead skin cells, promoting cell turnover and revealing fresher skin underneath.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T06:08:33.180Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Acne vulgaris"},{"name":"Photoaging and fine lines"},{"name":"Hyperpigmentation and melasma"},{"name":"Keratosis pilaris"},{"name":"Chemical peeling agent"}]},"trialDetails":[{"nctId":"NCT05362500","phase":"PHASE1","title":"Comparison of Chemical Peeling Agent With Transamine for Treatment of Melasma","status":"COMPLETED","sponsor":"Combined Military Hospital Abbottabad","startDate":"2021-06-01","conditions":"Melasma","enrollment":54},{"nctId":"NCT04359485","phase":"NA","title":"New Score for Pseudo- Acanthosis Nigricans","status":"UNKNOWN","sponsor":"Kasr El Aini Hospital","startDate":"2019-08-01","conditions":"Pseudo Acanthosis Nigricans","enrollment":20},{"nctId":"NCT03197883","phase":"NA","title":"Assessment of the Cosmetic Benefit of a Skin Cream in Healthy Females With Mild to Advanced Photo-damaged Facial Skin Who Have Undergone a Glycolic Acid Facial Peel Procedure","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2017-07-17","conditions":"Skin Care","enrollment":123},{"nctId":"NCT03103906","phase":"NA","title":"Evaluation of the Cosmetic Benefit of a Skin Cream in Healthy Females With Mild to Advanced Photo-damaged Facial Skin Who Have Undergone a Glycolic Acid Facial Peel Procedure","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2017-05-10","conditions":"Skin Care","enrollment":106},{"nctId":"NCT03548272","phase":"PHASE4","title":"BiOSS LIM C vs 2nd Generation DES in Non-LM Bifurcations","status":"UNKNOWN","sponsor":"Central Clinical Hospital of the Ministry of Internal Affairs and Administration, Warsaw, Poland","startDate":"2018-06-12","conditions":"Coronary Artery Disease","enrollment":518},{"nctId":"NCT03153852","phase":"PHASE4","title":"Modified Jessner's Solution With Trichloroacetic Acid Versus Glycolic Acid With Trichloroacetic Acid","status":"UNKNOWN","sponsor":"Assiut University","startDate":"2018-03-15","conditions":"Melasma","enrollment":30},{"nctId":"NCT02126644","phase":"PHASE2","title":"The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Photoaging","status":"UNKNOWN","sponsor":"National University Hospital, Singapore","startDate":"2014-05","conditions":"Photoaging","enrollment":10},{"nctId":"NCT02126657","phase":"PHASE2","title":"The Efficacy and Safety of a Single 70% Glycolic Acid Peel With Vitamin C for the Treatment of Acne Scars","status":"UNKNOWN","sponsor":"National University Hospital, Singapore","startDate":"2014-05","conditions":"Acne Scars","enrollment":10}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":9,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["Peeling agent"],"phase":"marketed","status":"active","brandName":"Glycolic Acid 70%","genericName":"Glycolic Acid 70%","companyName":"Combined Military Hospital Abbottabad","companyId":"combined-military-hospital-abbottabad","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Glycolic acid is an alpha-hydroxy acid (AHA) that exfoliates the skin by dissolving the bonds between dead skin cells, promoting cell turnover and revealing fresher skin underneath. Used for Acne vulgaris, Photoaging and fine lines, Hyperpigmentation and melasma.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}