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Glycerol and paracetamol
Glycerol and paracetamol is a Combination analgesic and osmotic agent Small molecule drug developed by Kamuzu University of Health Sciences. It is currently in Phase 3 development for Symptomatic relief of fever and pain (specific indication unclear from available information).
Glycerol provides osmotic hydration and paracetamol reduces fever and pain through cyclooxygenase inhibition.
Glycerol provides osmotic hydration and paracetamol reduces fever and pain through cyclooxygenase inhibition. Used for Symptomatic relief of fever and pain (specific indication unclear from available information).
At a glance
| Generic name | Glycerol and paracetamol |
|---|---|
| Sponsor | Kamuzu University of Health Sciences |
| Drug class | Combination analgesic and osmotic agent |
| Modality | Small molecule |
| Therapeutic area | Symptomatic relief / General supportive care |
| Phase | Phase 3 |
Mechanism of action
This is a combination product where glycerol acts as an osmotic agent and humectant to maintain hydration and potentially improve mucosal function, while paracetamol (acetaminophen) inhibits prostaglandin synthesis to reduce fever and mild-to-moderate pain. The combination appears designed for symptomatic relief in conditions where both hydration support and analgesic/antipyretic effects are beneficial.
Approved indications
- Symptomatic relief of fever and pain (specific indication unclear from available information)
Common side effects
- Gastrointestinal disturbance (from glycerol)
- Hepatotoxicity (paracetamol at high doses)
- Rash or hypersensitivity
Key clinical trials
- Diet Oil Induced Stimulation of GLP-1 (EARLY_PHASE1)
- Oral Glycerol and High-Dose Rectal Paracetamol to Improve the Prognosis of Childhood Bacterial Meningitis (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Glycerol and paracetamol CI brief — competitive landscape report
- Glycerol and paracetamol updates RSS · CI watch RSS
- Kamuzu University of Health Sciences portfolio CI
Frequently asked questions about Glycerol and paracetamol
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Related
- Drug class: All Combination analgesic and osmotic agent drugs
- Manufacturer: Kamuzu University of Health Sciences — full pipeline
- Therapeutic area: All drugs in Symptomatic relief / General supportive care
- Indication: Drugs for Symptomatic relief of fever and pain (specific indication unclear from available information)
- Compare: Glycerol and paracetamol vs similar drugs
- Pricing: Glycerol and paracetamol cost, discount & access