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glulisine insulin, glargine insulin
glulisine insulin, glargine insulin is a insulin analog Small molecule drug developed by Population Health Research Institute. It is currently in Phase 3 development for Type 1 diabetes, Type 2 diabetes. Also known as: Apidra, Lantus.
Glulisine insulin and glargine insulin are long-acting insulin analogs that mimic the action of human insulin, stimulating glucose uptake in cells and lowering blood glucose levels.
Glulisine insulin and glargine insulin are long-acting insulin analogs that mimic the action of human insulin, stimulating glucose uptake in cells and lowering blood glucose levels. Used for Type 1 diabetes, Type 2 diabetes.
At a glance
| Generic name | glulisine insulin, glargine insulin |
|---|---|
| Also known as | Apidra, Lantus |
| Sponsor | Population Health Research Institute |
| Drug class | insulin analog |
| Target | insulin receptor |
| Modality | Small molecule |
| Therapeutic area | Diabetes |
| Phase | Phase 3 |
Mechanism of action
Glulisine insulin and glargine insulin work by binding to insulin receptors on the surface of cells, triggering a signaling cascade that ultimately leads to the uptake of glucose from the bloodstream into cells. This process helps to lower blood glucose levels and improve glycemic control.
Approved indications
- Type 1 diabetes
- Type 2 diabetes
Common side effects
- Hypoglycemia
- Weight gain
- Allergic reactions
Key clinical trials
- Evaluation of Insulin Glulisine (GP40321) Compared to Insulin Glulisine (Apidra® SoloStar®) in Type 1 Diabetes Mellitus Patients (PHASE3)
- Afrezza® INHALE-1 Study in Pediatrics (PHASE3)
- Degludec Glargine U300 Hospital Study (NA)
- Closed Loop From Onset in Type 1 Diabetes (NA)
- Dapagliflozin As Additional Treatment To Liraglutide And Insulin In Patients With Type 1 Diabetes (PHASE3)
- FLuctuATion Reduction With inSULin and Glp-1 Added togetheR (FLAT-SUGAR) (PHASE4)
- Comparison of Two Treatment Regimens in Patients With Type 2 Diabetes After Short-term Intensive Insulin Therapy (PHASE4)
- Efficacy and Safety of the Insulin Glargine/Lixisenatide Fixed Ratio Combination Versus Insulin Glargine in Patients With Type 2 Diabetes (LixiLan-India) (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- glulisine insulin, glargine insulin CI brief — competitive landscape report
- glulisine insulin, glargine insulin updates RSS · CI watch RSS
- Population Health Research Institute portfolio CI
Frequently asked questions about glulisine insulin, glargine insulin
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Related
- Drug class: All insulin analog drugs
- Target: All drugs targeting insulin receptor
- Manufacturer: Population Health Research Institute — full pipeline
- Therapeutic area: All drugs in Diabetes
- Indication: Drugs for Type 1 diabetes
- Indication: Drugs for Type 2 diabetes
- Also known as: Apidra, Lantus
- Compare: glulisine insulin, glargine insulin vs similar drugs
- Pricing: glulisine insulin, glargine insulin cost, discount & access