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Ginkgo Biloba Extract (GBE)
Ginkgo biloba extract improves blood flow and reduces oxidative stress through antioxidant and antiplatelet mechanisms.
Ginkgo biloba extract improves blood flow and reduces oxidative stress through antioxidant and antiplatelet mechanisms. Used for Age-related cognitive decline and dementia, Peripheral arterial occlusive disease, Tinnitus.
At a glance
| Generic name | Ginkgo Biloba Extract (GBE) |
|---|---|
| Also known as | Cerenin(Ginkgo Biloba Extract) film-coated 40 mg |
| Sponsor | Taipei Veterans General Hospital, Taiwan |
| Drug class | Herbal extract / Nootropic |
| Modality | Small molecule |
| Therapeutic area | Neurology / Cardiovascular |
| Phase | FDA-approved |
Mechanism of action
GBE contains flavonoids and terpenoids that act as free radical scavengers and inhibit platelet-activating factor, thereby enhancing cerebral and peripheral microcirculation. It also modulates neurotransmitter function and reduces neuroinflammation, which may contribute to cognitive and vascular benefits.
Approved indications
- Age-related cognitive decline and dementia
- Peripheral arterial occlusive disease
- Tinnitus
- Vertigo and dizziness
Common side effects
- Headache
- Gastrointestinal upset
- Dizziness
- Bleeding risk (with anticoagulants)
Key clinical trials
- To Evaluate the Effect of Ginkgo Biloba Extract on Optic Nerve Head Perfusion Examined Using OCTA (PHASE4)
- The Effect of PAP on ISSHL Comorbided With OSA (PHASE4)
- Effect of Ginkgo Biloba Special Extract LI 1370 on Dual-tasking in Patients With MCI (PHASE4)
- Study Effects of Ginkgo Biloba Extract on Endothelial Cell Function and Genetic Effects on the Response to Ginkgo Biloba Extract in Diabetic Patients With Stable Coronary Artery Disease (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |