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Gensigen (gentisic acid)
Gensigen (generic name: gentisic acid) is a gentisic acid drug. It is currently in unknown development.
Gensigen works by blocking the enzyme carbonic anhydrase 2, which helps regulate the balance of fluids and electrolytes in the body.
Gentisic acid is a dihydroxybenzoic acid and a derivative of benzoic acid, which is a minor product of the metabolic breakdown of aspirin. It is excreted by the kidneys.
At a glance
| Generic name | gentisic acid |
|---|---|
| Drug class | gentisic acid |
| Target | Arachidonate 5-lipoxygenase, Carbonic anhydrase 1, Carbonic anhydrase 12 |
| Therapeutic area | Other |
| Phase | unknown |
Mechanism of action
Think of carbonic anhydrase 2 like a pump that helps move fluids and electrolytes in and out of cells. When gensigen blocks this pump, it can affect the balance of fluids and electrolytes in the body, which can be helpful in treating certain conditions. However, this can also lead to side effects if not managed properly.
Approved indications
Common side effects
Key clinical trials
- 177Lu-DOTA-EB-TATE in Adult Patients With Metastatic, Radioactive Iodine Non-Responsive Oncocytic (Hurthle-Cell) Thyroid Cancer (PHASE1,PHASE2)
- Use of 68Ga-dotatate PET Scan in Neuroendocrine Carcinoma of the GI Tract
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Gensigen CI brief — competitive landscape report
- Gensigen updates RSS · CI watch RSS
- portfolio CI
Frequently asked questions about Gensigen
What is Gensigen?
How does Gensigen work?
What is the generic name of Gensigen?
What drug class is Gensigen in?
What development phase is Gensigen in?
What does Gensigen target?
Related
- Drug class: All gentisic acid drugs
- Target: All drugs targeting Arachidonate 5-lipoxygenase, Carbonic anhydrase 1, Carbonic anhydrase 12
- Manufacturer: — full pipeline
- Therapeutic area: All drugs in Other
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing