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8-Fluoroerythromycin (FLURITHROMYCIN)

Phase 2 active Small molecule Quality 24/100

8-Fluoroerythromycin (generic name: FLURITHROMYCIN) is a flurithromycin drug. It is currently in Phase 2 development.

Flurithromycin works by binding to the bacterial ribosome and inhibiting the action of the 50S subunit, thereby preventing the synthesis of essential bacterial proteins.

8-Fluoroerythromycin, also known as Flurithromycin, is a small molecule antibiotic belonging to the drug class of flurithromycin. Its exact target is unknown, but it is believed to work by inhibiting bacterial protein synthesis. Flurithromycin is not FDA-approved for any indications, and its commercial status is unclear. As a result, there is limited information available on its safety profile and pharmacokinetic properties. Further research is needed to fully understand the potential benefits and risks of this antibiotic.

Likelihood of approval
17.3% vs 15.3% industry baseline
If approved by FDA: likely 2031–2034
Steps remaining: Phase 3 → NDA/BLA submission
Confidence: Medium
Why this estimate
  • Baseline phase 2 → approval rate +15.3pp
    Industry-wide phase 2 drugs reach approval ~15.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
  • Anti-infectives pathway favourability +2.0pp
    Microbiological endpoints + non-inferiority designs raise approval rates above baseline.
Predicted approval windows by jurisdiction (conditional on FDA approval)
Regulator Country Likely year Lag vs FDA
FDA US 2031–2034
EMA EU 2032–2035 +0.7 yr
MHRA GB 2032–2035 +0.7 yr
Health Canada CA 2032–2036 +0.9 yr
TGA AU 2032–2036 +1.2 yr
PMDA JP 2032–2036 +1.5 yr
NMPA CN 2033–2037 +2.3 yr
MFDS KR 2032–2036 +1.4 yr
CDSCO IN 2032–2037 +1.8 yr
ANVISA BR 2033–2037 +2.3 yr

Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).

Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.

At a glance

Generic nameFLURITHROMYCIN
Drug classflurithromycin
ModalitySmall molecule
Therapeutic areaInfectious Disease
PhasePhase 2

Mechanism of action

Imagine your body's cells are like factories that make proteins to keep you healthy. Bacteria are like tiny factories that make proteins to harm you. Flurithromycin is a special tool that blocks the bacterial factories from making proteins, ultimately killing the bacteria and helping to fight off infections.

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Frequently asked questions about 8-Fluoroerythromycin

What is 8-Fluoroerythromycin?

8-Fluoroerythromycin (FLURITHROMYCIN) is a flurithromycin drug.

How does 8-Fluoroerythromycin work?

Flurithromycin works by binding to the bacterial ribosome and inhibiting the action of the 50S subunit, thereby preventing the synthesis of essential bacterial proteins.

What is the generic name of 8-Fluoroerythromycin?

FLURITHROMYCIN is the generic (nonproprietary) name of 8-Fluoroerythromycin.

What drug class is 8-Fluoroerythromycin in?

8-Fluoroerythromycin belongs to the flurithromycin class. See all flurithromycin drugs at /class/flurithromycin.

What development phase is 8-Fluoroerythromycin in?

8-Fluoroerythromycin is in Phase 2.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing