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Fenretinide Lym-X-Sorb Oral Powder
Fenretinide Lym-X-Sorb Oral Powder is a retinoid Small molecule drug developed by South Plains Oncology Consortium. It is currently in Phase 2 development for Metastatic breast cancer. Also known as: 4-HPR, Fenretinide, 4-HPR/LXS, Fenretinide/LXS.
Fenretinide is a synthetic retinoid that induces apoptosis in cancer cells.
Fenretinide is a synthetic retinoid that induces apoptosis in cancer cells. Used for Metastatic breast cancer.
At a glance
| Generic name | Fenretinide Lym-X-Sorb Oral Powder |
|---|---|
| Also known as | 4-HPR, Fenretinide, 4-HPR/LXS, Fenretinide/LXS |
| Sponsor | South Plains Oncology Consortium |
| Drug class | retinoid |
| Target | retinoic acid receptor |
| Modality | Small molecule |
| Therapeutic area | Oncology |
| Phase | Phase 2 |
Mechanism of action
Fenretinide works by activating retinoic acid receptors, which leads to the induction of apoptosis in cancer cells. This process is thought to be mediated by the activation of caspases and the disruption of mitochondrial function.
Approved indications
- Metastatic breast cancer
Common side effects
- Nausea
- Vomiting
- Fatigue
Key clinical trials
- N2004-04: Fenretinide LXS in Treating Patients With Recurrent, Refractory, or Persistent Neuroblastoma (PHASE1)
- Fenretinide Lym-X-Sorb + Ketoconazole + Vincristine for Recurrent or Resistant Neuroblastoma (PHASE1)
- Expanded Access Study of Fenretinide Lym-X-Sorb Plus Ketoconazole in Neuroblastoma
- Fenretinide/LXS Oral Powder Plus Ketoconazole in Recurrent Ovarian Cancer (PHASE1, PHASE2)
- Fenretinide Lym-X-Sorb™ in Treating Patients With Recurrent or Resistant Solid Tumors or Lymphoma (PHASE1)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Fenretinide Lym-X-Sorb Oral Powder CI brief — competitive landscape report
- Fenretinide Lym-X-Sorb Oral Powder updates RSS · CI watch RSS
- South Plains Oncology Consortium portfolio CI
Frequently asked questions about Fenretinide Lym-X-Sorb Oral Powder
What is Fenretinide Lym-X-Sorb Oral Powder?
How does Fenretinide Lym-X-Sorb Oral Powder work?
What is Fenretinide Lym-X-Sorb Oral Powder used for?
Who makes Fenretinide Lym-X-Sorb Oral Powder?
Is Fenretinide Lym-X-Sorb Oral Powder also known as anything else?
What drug class is Fenretinide Lym-X-Sorb Oral Powder in?
What development phase is Fenretinide Lym-X-Sorb Oral Powder in?
What are the side effects of Fenretinide Lym-X-Sorb Oral Powder?
What does Fenretinide Lym-X-Sorb Oral Powder target?
Related
- Drug class: All retinoid drugs
- Target: All drugs targeting retinoic acid receptor
- Manufacturer: South Plains Oncology Consortium — full pipeline
- Therapeutic area: All drugs in Oncology
- Indication: Drugs for Metastatic breast cancer
- Also known as: 4-HPR, Fenretinide, 4-HPR/LXS, Fenretinide/LXS
- Compare: Fenretinide Lym-X-Sorb Oral Powder vs similar drugs
- Pricing: Fenretinide Lym-X-Sorb Oral Powder cost, discount & access