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F-choline intravenous injection
F-choline is a fluorine-18 labeled choline analog used as a positron emission tomography (PET) imaging agent to visualize choline metabolism in tissues.
F-choline is a fluorine-18 labeled choline analog used as a positron emission tomography (PET) imaging agent to visualize choline metabolism in tissues. Used for PET imaging of prostate cancer, PET imaging of other malignancies with elevated choline metabolism.
At a glance
| Generic name | F-choline intravenous injection |
|---|---|
| Also known as | Fluorocholine |
| Sponsor | Centre hospitalier de l'Université de Montréal (CHUM) |
| Drug class | PET imaging agent |
| Target | Choline transporters |
| Modality | Small molecule |
| Therapeutic area | Oncology |
| Phase | Phase 3 |
Mechanism of action
F-choline accumulates in cells with high choline uptake and metabolism, particularly in tumors and areas of inflammation. The fluorine-18 radiolabel allows detection via PET imaging, enabling visualization of metabolically active lesions. This is used primarily for oncologic imaging to detect and stage malignancies.
Approved indications
- PET imaging of prostate cancer
- PET imaging of other malignancies with elevated choline metabolism
Common side effects
- Radiation exposure
- Injection site reactions
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
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