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Experimental Denture Adhesive
A denture adhesive formulation that enhances the mechanical retention and seal of dentures to oral tissues.
A denture adhesive formulation that enhances the mechanical retention and seal of dentures to oral tissues. Used for Denture retention and stability in edentulous patients.
At a glance
| Generic name | Experimental Denture Adhesive |
|---|---|
| Sponsor | GlaxoSmithKline |
| Modality | Small molecule |
| Therapeutic area | Dental/Oral Health |
| Phase | Phase 3 |
Mechanism of action
Denture adhesives work by creating a physical and chemical bond between the denture base and the underlying oral mucosa, improving retention, stability, and comfort during mastication and speech. This experimental formulation from GSK likely incorporates novel polymeric or adhesive components designed to improve biocompatibility, duration of hold, or ease of removal compared to existing products.
Approved indications
- Denture retention and stability in edentulous patients
Common side effects
- Oral irritation or mucosal sensitivity
- Difficulty with denture removal
- Taste alteration
Key clinical trials
- A Clinical Study Assessing the Maximum Maxillary Bite Force When Using Three Denture Adhesives Compared to Using No-Adhesive (NA)
- Clinical Study of a 3D Shaded Zirconia for Chairside CAD/CAM Restorations
- Comparative Evaluation of Clinical and Radiographic Treatment Outcomes of Garlic Gel and Calcium Hydroxide as an Intracanal Medicament in Nonsurgical Root Canal Treatment of Permanent Teeth. (PHASE3)
- Efficacy and Safety Evaluation Study of Implants With Periodontal Ligament (NA)
- Effects of the Use of an Immersive Virtual Reality Device on Handwriting in Children Aged 6 to 13 With Handwriting Difficulties ( RVALIGO ) (NA)
- Postoperative Pain After Pulpotomy in Children Using Calcium Silicate Cements With and Without Laser Therapy (NA)
- Kinesiotherapy on Upper Limb Function and Activities of Daily Living in Children With Hemiplegic Cerebral Palsy (NA)
- Using Platelet-rich Fibrin in Regenerative Endodontic Treatment in Mature Permanent Teeth (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Experimental Denture Adhesive CI brief — competitive landscape report
- Experimental Denture Adhesive updates RSS · CI watch RSS
- GlaxoSmithKline portfolio CI