Last reviewed 2026-05-25 · How we verify

Acriflavine (euflavine)

unknown active ✓ Verified May 2026

Acriflavine (generic name: euflavine) is a euflavine drug. It is currently in unknown development.

Acriflavine works by binding to and inhibiting hypoxia-inducible factor 1-alpha, a protein that helps cells adapt to low oxygen levels.

Acriflavine is an antiseptic and disinfectant, as classified by Wikipedia. It is being studied in combination with other treatments for urinary tract infections, specifically in the clinical trial "Clinical Assessment of Urinary Antiseptics Methenamine and Methylthioninium in Recurrent Cystitis" (NCT03379389).

At a glance

Generic name	euflavine
Drug class	euflavine
Target	Hypoxia-inducible factor 1-alpha, ORF 73
Therapeutic area	Oncology
Phase	unknown

Mechanism of action

Think of hypoxia-inducible factor 1-alpha like a switch that helps cells survive in low-oxygen environments. Acriflavine turns off this switch, which can help prevent the growth of certain types of cancer cells that thrive in low-oxygen conditions.

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Key clinical trials

Clinical Assessment of Urinary Antiseptics Methenamine and Methylthioninium in Recurrent Cystitis (PHASE4)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

Source	Used for
ClinicalTrials.gov	Trial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Acriflavine CI brief — competitive landscape report
Acriflavine updates RSS · CI watch RSS
portfolio CI

Frequently asked questions about Acriflavine

What is Acriflavine?

Acriflavine (euflavine) is a euflavine drug.

How does Acriflavine work?

Acriflavine works by binding to and inhibiting hypoxia-inducible factor 1-alpha, a protein that helps cells adapt to low oxygen levels.

What is the generic name of Acriflavine?

euflavine is the generic (nonproprietary) name of Acriflavine.

What drug class is Acriflavine in?

Acriflavine belongs to the euflavine class. See all euflavine drugs at /class/euflavine.

What development phase is Acriflavine in?

Acriflavine is in unknown.

What does Acriflavine target?

Acriflavine targets Hypoxia-inducible factor 1-alpha, ORF 73 and is a euflavine.

Drug class: All euflavine drugs
Target: All drugs targeting Hypoxia-inducible factor 1-alpha, ORF 73
Manufacturer: — full pipeline
Therapeutic area: All drugs in Oncology

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing