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Enteral nutrition alanyl-glutamin, Dipeptiven

Enteral nutrition alanyl-glutamin, Dipeptiven is a Amino acid supplement / Nutritional therapy Small molecule drug developed by University Hospital, Clermont-Ferrand. It is currently in Phase 3 development for Enteral nutritional support in critically ill patients, Post-operative nutritional support, Patients at risk of glutamine depletion during metabolic stress. Also known as: All patients will received, whatever treatment arm, intravenous alanyl-glutamin, Dipeptiven which have AMM..

Alanyl-glutamine is a dipeptide that provides glutamine and alanine as substrates to support protein synthesis, immune function, and gut barrier integrity in critically ill or malnourished patients receiving enteral nutrition.

Alanyl-glutamine is a dipeptide that provides glutamine and alanine as substrates to support protein synthesis, immune function, and gut barrier integrity in critically ill or malnourished patients receiving enteral nutrition. Used for Enteral nutritional support in critically ill patients, Post-operative nutritional support, Patients at risk of glutamine depletion during metabolic stress.

At a glance

Mechanism of action

Glutamine is a conditionally essential amino acid that becomes depleted during critical illness and serves as a primary fuel for enterocytes and immune cells. Alanyl-glutamine (Dipeptiven) delivers glutamine in a stable dipeptide form that can be added to enteral nutrition formulations, bypassing the instability of free glutamine and supporting intestinal mucosal integrity, immune cell proliferation, and overall protein metabolism during periods of metabolic stress.

Approved indications

• Enteral nutritional support in critically ill patients
• Post-operative nutritional support
• Patients at risk of glutamine depletion during metabolic stress

Common side effects

• Gastrointestinal tolerance issues
• Hyperglycemia

Key clinical trials

• Randomized, Prospective, Multicenter Study to Compare Enteral Nutrition to Parenteral Nutrition as Feeding Support in Patients Presenting Malignant Hemopathy Who Underwent an Allogeneic Hematopoietic Stem Cell Transplantation. (PHASE3)

Primary sources

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Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

• Enteral nutrition alanyl-glutamin, Dipeptiven CI brief — competitive landscape report
• Enteral nutrition alanyl-glutamin, Dipeptiven updates RSS · CI watch RSS
• University Hospital, Clermont-Ferrand portfolio CI

Frequently asked questions about Enteral nutrition alanyl-glutamin, Dipeptiven

Related

• Drug class: All Amino acid supplement / Nutritional therapy drugs
• Manufacturer: University Hospital, Clermont-Ferrand — full pipeline
• Therapeutic area: All drugs in Critical Care / Nutritional Support
• Indication: Drugs for Enteral nutritional support in critically ill patients
• Indication: Drugs for Post-operative nutritional support
• Indication: Drugs for Patients at risk of glutamine depletion during metabolic stress
• Also known as: All patients will received, whatever treatment arm, intravenous alanyl-glutamin, Dipeptiven which have AMM.
• Compare: Enteral nutrition alanyl-glutamin, Dipeptiven vs similar drugs
• Pricing: Enteral nutrition alanyl-glutamin, Dipeptiven cost, discount & access