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Endodontic treatment using Vitapex
Vitapex is a calcium hydroxide-based root canal filling material that provides antimicrobial action and promotes healing in endodontic treatment.
Vitapex is a calcium hydroxide-based root canal filling material that provides antimicrobial action and promotes healing in endodontic treatment. Used for Root canal treatment and obturation in primary and permanent teeth, Endodontic therapy for infected or necrotic pulp.
At a glance
| Generic name | Endodontic treatment using Vitapex |
|---|---|
| Sponsor | Fausto Medeiros Mendes |
| Drug class | Endodontic filling material |
| Modality | Small molecule |
| Therapeutic area | Dentistry / Endodontics |
| Phase | Phase 3 |
Mechanism of action
Vitapex is a premeasured, injectable calcium hydroxide paste combined with iodoform that is delivered through a plastic carrier into the root canal system. The calcium hydroxide component provides alkaline pH to neutralize bacterial acids and promote periapical healing, while the iodoform provides radiopacity and additional antimicrobial properties. The system allows for precise, three-dimensional obturation of the root canal space.
Approved indications
- Root canal treatment and obturation in primary and permanent teeth
- Endodontic therapy for infected or necrotic pulp
Common side effects
- Periapical inflammation
- Allergic reaction to iodoform
- Extrusion beyond apex
Key clinical trials
- Endodontic Treatment of Necrotic Primary Teeth With Guedes Pinto Paste: A Randomized Clinical Trial (PHASE3)
- Endodontic Treatment of Primary Teeth Using Mineral Trioxide Aggregate Paste (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Endodontic treatment using Vitapex CI brief — competitive landscape report
- Endodontic treatment using Vitapex updates RSS · CI watch RSS
- Fausto Medeiros Mendes portfolio CI