Last reviewed · How we verify
EMONO
EMONO is a medical gas mixture (likely nitric oxide-based) designed to improve oxygenation and reduce pulmonary hypertension in critically ill patients.
EMONO is a medical gas mixture (likely nitric oxide-based) designed to improve oxygenation and reduce pulmonary hypertension in critically ill patients. Used for Acute respiratory distress syndrome (ARDS) or severe hypoxemia (Phase 3 indication pending confirmation).
At a glance
| Generic name | EMONO |
|---|---|
| Also known as | Nitrous Oxide/Oxygen, Nitrous oxide |
| Sponsor | Air Liquide Santé International |
| Drug class | Therapeutic gas |
| Modality | Small molecule |
| Therapeutic area | Critical Care / Pulmonary |
| Phase | Phase 3 |
Mechanism of action
Air Liquide Santé International's EMONO appears to be a therapeutic gas product, potentially containing nitric oxide or similar gaseous agents that act on vascular endothelium to promote vasodilation and improve gas exchange. The exact mechanism requires confirmation from clinical trial data, but therapeutic gases in this class typically work by modulating nitric oxide signaling pathways or improving oxygen delivery to tissues.
Approved indications
- Acute respiratory distress syndrome (ARDS) or severe hypoxemia (Phase 3 indication pending confirmation)
Common side effects
- Methemoglobinemia
- Nitrogen dioxide exposure toxicity
Key clinical trials
- Efficacy on Anxiety of the Digital Music Application Versus Equimolar Mixture of Oxygen and Nitrous Oxide in Patients Receiving CT-guided Lumbar Infiltration (NA)
- Evaluation of Paro, a Therapeutic Assistance Robot in Analgesic Management During the Placement of a Peripheral Intravenous Line in Infants and Children. (NA)
- Nitrous Oxide for Late-Life Depression - PROTO-BRAIN (NA)
- Efficacy of EMONO as an add-on Therapy to Conventional Antidepressants for the Treatment of Depressive Symptoms in Nursing-home Residents With Neurocognitive Disorders: a Randomized Controlled Trial- (PHASE2)
- Use of the Equimolar Mixture of Oxide Nitrous and Oxygen (EMONO) Associated With Audiovisuals in Children (NA)
- Evaluation of the Efficacy of Intra-nasal Sufentanil for Analgesia of Vaso-occlusive Crisis in Sickle-cell Adults. (PHASE3)
- Evaluation Ofe the Anxiolytic Effect of EMONO in Children During Dental Care (MOPEA)
- Effects of EMONO in Children During Dental Care
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |