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elmex® gelée

Gaba International AG · FDA-approved active Small molecule

elmex® gelée is a topical fluoride gel that strengthens tooth enamel and prevents dental caries by promoting remineralization and inhibiting bacterial acid production.

elmex® gelée is a topical fluoride gel that strengthens tooth enamel and prevents dental caries by promoting remineralization and inhibiting bacterial acid production. Used for Prevention of dental caries (cavities), Enamel remineralization and strengthening.

At a glance

Generic nameelmex® gelée
Also known aselmex® gel
SponsorGaba International AG
Drug classTopical fluoride agent
TargetTooth enamel hydroxyapatite; bacterial glycolytic enzymes
ModalitySmall molecule
Therapeutic areaDental/Oral Health
PhaseFDA-approved

Mechanism of action

The gel contains sodium fluoride as its active ingredient, which penetrates the enamel surface and facilitates the incorporation of fluoride into the hydroxyapatite crystal structure, making teeth more resistant to demineralization. It also reduces the metabolic activity of cariogenic bacteria, thereby decreasing acid production. Regular application helps reverse early enamel demineralization and prevent cavity formation.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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