{"id":"elmex-gel-e","safety":{"commonSideEffects":[{"rate":null,"effect":"Dental fluorosis (with excessive ingestion)"},{"rate":null,"effect":"Mild irritation or sensitivity"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"The gel contains sodium fluoride as its active ingredient, which penetrates the enamel surface and facilitates the incorporation of fluoride into the hydroxyapatite crystal structure, making teeth more resistant to demineralization. It also reduces the metabolic activity of cariogenic bacteria, thereby decreasing acid production. Regular application helps reverse early enamel demineralization and prevent cavity formation.","oneSentence":"elmex® gelée is a topical fluoride gel that strengthens tooth enamel and prevents dental caries by promoting remineralization and inhibiting bacterial acid production.","_ai_confidence":"high"},"_scrapedAt":"2026-03-27T23:45:19.734Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of dental caries (cavities)"},{"name":"Enamel remineralization and strengthening"}]},"trialDetails":[{"nctId":"NCT01329731","phase":"PHASE4","title":"Remineralisation of White Spot Lesions by Elmex® gelée in Post-orthodontic Patients","status":"COMPLETED","sponsor":"Gaba International AG","startDate":"2011-03","conditions":"Tooth; Lesion, White Spot Lesions","enrollment":48}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":24,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["elmex® gel"],"phase":"marketed","status":"active","brandName":"elmex® gelée","genericName":"elmex® gelée","companyName":"Gaba International AG","companyId":"gaba-international-ag","modality":"Small molecule","firstApprovalDate":"","aiSummary":"elmex® gelée is a topical fluoride gel that strengthens tooth enamel and prevents dental caries by promoting remineralization and inhibiting bacterial acid production. Used for Prevention of dental caries (cavities), Enamel remineralization and strengthening.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}