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Efgartigimod IV or Efgartigimod PH20 SC
Efgartigimod IV or Efgartigimod PH20 SC is a Monoclonal antibody Biologic drug developed by argenx. It is currently in Phase 2 development for Myasthenia Gravis.
Monoclonal antibody targeting muscle relaxant proteins
Monoclonal antibody targeting muscle relaxant proteins Used for Myasthenia Gravis.
At a glance
| Generic name | Efgartigimod IV or Efgartigimod PH20 SC |
|---|---|
| Sponsor | argenx |
| Drug class | Monoclonal antibody |
| Target | MuSK and LRP4 |
| Modality | Biologic |
| Therapeutic area | Neurology |
| Phase | Phase 2 |
Mechanism of action
Efgartigimod is a human IgG1 antibody that targets and depletes muscle relaxant proteins, including muscle-specific kinase (MuSK) and low-density lipoprotein receptor-related protein 4 (LRP4).
Approved indications
- Myasthenia Gravis
Common side effects
- Injection site reaction
- Headache
- Fatigue
Key clinical trials
- A Worldwide Pregnancy Safety Study to Assess Maternal, Fetal, and Infant Outcomes Following Exposure to Efgartigimod During Pregnancy and/or Breastfeeding.
- Evaluating Long-term Safety of Efgartigimod Administered Intravenously and Efgartigimod PH20 Administered Subcutaneously in Children With Generalized Myasthenia Gravis (PHASE2, PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Efgartigimod IV or Efgartigimod PH20 SC CI brief — competitive landscape report
- Efgartigimod IV or Efgartigimod PH20 SC updates RSS · CI watch RSS
- argenx portfolio CI
Frequently asked questions about Efgartigimod IV or Efgartigimod PH20 SC
What is Efgartigimod IV or Efgartigimod PH20 SC?
How does Efgartigimod IV or Efgartigimod PH20 SC work?
What is Efgartigimod IV or Efgartigimod PH20 SC used for?
Who makes Efgartigimod IV or Efgartigimod PH20 SC?
What drug class is Efgartigimod IV or Efgartigimod PH20 SC in?
What development phase is Efgartigimod IV or Efgartigimod PH20 SC in?
What are the side effects of Efgartigimod IV or Efgartigimod PH20 SC?
What does Efgartigimod IV or Efgartigimod PH20 SC target?
Related
- Drug class: All Monoclonal antibody drugs
- Target: All drugs targeting MuSK and LRP4
- Manufacturer: argenx — full pipeline
- Therapeutic area: All drugs in Neurology
- Indication: Drugs for Myasthenia Gravis
- Compare: Efgartigimod IV or Efgartigimod PH20 SC vs similar drugs
- Pricing: Efgartigimod IV or Efgartigimod PH20 SC cost, discount & access