Vyvgart · Immunology · revenue 2500 Vyvgart works by binding to the p51 subunit of the FcRn receptor, preventing it from recycling antibodies back into the bloodstream.
Efgartigimod PH20 SC · Immunology Efgartigimod is an IgG Fc fragment that binds to the neonatal Fc receptor (FcRn) to reduce circulating immunoglobulin levels, particularly IgG antibodies.
Phase 3 pipeline
ARGX-113 · Immunology ARGX-113 is a monoclonal antibody that blocks the neonatal Fc receptor (FcRn) to reduce circulating immunoglobulin levels, particularly IgG antibodies.
efgartigimod IV · Immunology Efgartigimod IV is a monoclonal antibody that targets and depletes neonatal Fc receptor (FcRn), thereby reducing the levels of immunoglobulin G (IgG) in the body.
Empasiprubart IV · Immunology Empasiprubart is a FcRn (neonatal Fc receptor) antagonist that reduces the recycling and extends the half-life of IgG antibodies, enhancing their therapeutic activity.
Phase 2 pipeline
ARGX-117 · Autoimmune diseases ARGX-117 is a monoclonal antibody targeting CD70.
ARGX-119 IV · Autoimmune diseases ARGX-119 IV is a monoclonal antibody targeting CD70.
EFG PH20 SC · Neurology EFG PH20 SC is a monoclonal antibody targeting ephrin type-A receptor 4 (EphA4).