Last reviewed · How we verify
Effexor
At a glance
| Generic name | Effexor |
|---|---|
| Sponsor | Wyeth is now a wholly owned subsidiary of Pfizer |
| Target | 5-hydroxytryptamine receptor 6, 5-hydroxytryptamine receptor 2A, 5-hydroxytryptamine receptor 2C |
| Modality | Small molecule |
| Therapeutic area | Neuroscience |
| Phase | FDA-approved |
Approved indications
- Generalized anxiety disorder
- Major depressive disorder
- Panic disorder
- Social phobia
Common side effects
- Nausea
- Insomnia
- Dizziness
- Somnolence
- Dry mouth
- Asthenia
- Sweating (including night sweats)
- Anorexia
- Abnormal ejaculation/orgasm (men)
- Constipation
- Nervousness
- Diarrhea
Serious adverse events
- Impotence (men)
- Libido decreased
- Anorgasmia (women)
- Palpitation
- Paresthesia
Key clinical trials
- Venlafaxine as Adjunct Therapy in Rheumatoid Arthritis (PHASE2)
- The Analgesic Efficacy and Safety of Venlafaxine for Prevention of Postherpetic Neuralgia in Patients With Acute Herpes Zoster (NA)
- A Study Following Women in Menopause Treated With a Non-hormonal Therapy for Hot Flashes and Night Sweats
- Pharmacokinetics and Safety of Commonly Used Drugs in Lactating Women and Breastfed Infants
- The Efficacy and Safety of Short Term S-ketamine Infusion as an Adjunctive Therapy in Patients With Fibromyalgia (NA)
- The Analgesic Efficacy and Safety of Desvenlafaxine in Patients With Herpes Zoster (NA)
- Intensified Pharmacological Treatment for Schizophrenia, Major Depressive Disorder and Bipolar Depression After a First-time Treatment Failure (PHASE3)
- Desvenlafaxine for Preventive Treatment of Frequent Episodic Tension-type Headache (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Effexor CI brief — competitive landscape report
- Effexor updates RSS · CI watch RSS
- Wyeth is now a wholly owned subsidiary of Pfizer portfolio CI