Wyeth is now a wholly owned subsidiary of Pfizer

Quick facts

Marketed products

• 7-valent pneumococcal conjugate vaccine
• Advante · Other
• ceftriaxone plus metronidazole
• ceftriaxone sodium + metronidazole · Infectious Disease
  This combination uses a third-generation cephalosporin to inhibit bacterial cell wall synthesis and a nitroimidazole to disrupt anaerobic bacterial DNA, providing broad-spectrum coverage against aerobic gram-negative, gram-positive, and anaerobic organisms.
• Effexor · Neuroscience
• Effexor® (Venlafaxine) · Psychiatry / Neurology
  Venlafaxine inhibits the reuptake of serotonin and norepinephrine in the central nervous system, increasing their availability at synaptic sites.
• etanercept (EnbrelTM) · Immunology
  Etanercept is a TNF receptor fusion protein that binds and neutralizes tumor necrosis factor (TNF), a key inflammatory cytokine driving immune-mediated diseases.
• Etanercept + Methotrexate · Immunology
  Etanercept blocks tumor necrosis factor (TNF) to reduce inflammation, while methotrexate suppresses immune cell proliferation; together they synergistically reduce joint inflammation and slow disease progression in rheumatoid arthritis.
• Factor IX recovery · Hematology
  Factor IX recovery refers to the measurement of how much functional Factor IX (a blood clotting protein) is present in the bloodstream after administration of a Factor IX replacement product.
• ibuprofen Formulation 1
• ibuprofen Formulation 2
• InductOs
• Levonorgestrel/Ethinyl Estradiol · Contraception / Gynecology
  This combination oral contraceptive suppresses ovulation by inhibiting the luteinizing hormone surge through progestin and estrogen feedback on the hypothalamic-pituitary axis.
• Meningococcal C · Immunology / Infectious Disease
  Meningococcal C conjugate vaccine stimulates the immune system to produce antibodies against Neisseria meningitidis serogroup C polysaccharide capsule.
• Methotrexate plus ENBREL or ENBREL alone
• Methotrexate; sulfasalazine; hydroxychloroquine;leflunomide
• Neoral® (Cyclosporine) · Immunology
  Cyclosporine inhibits T-cell activation by binding to cyclophilin and blocking calcineurin-mediated transcription of interleukin-2 and other cytokines.
• Perioperative Corticosteroids · Surgery/Perioperative Medicine
  Corticosteroids suppress the inflammatory and immune response by binding to glucocorticoid receptors, reducing the production of pro-inflammatory cytokines and mediators.
• pneumococcus conjugate vaccine
• Prevenar · Other
• Prevenar and Meningitec · Immunology / Infectious Disease
  These are conjugate vaccines that stimulate the immune system to produce antibodies against specific bacterial pathogens by linking polysaccharide antigens to protein carriers.
• Rapamune · Oncology
• Rapamune® (Sirolimus) · Immunology
  Sirolimus inhibits mTOR (mammalian target of rapamycin), a key signaling protein that controls cell growth and proliferation, thereby suppressing immune cell activation and reducing organ rejection.
• Recombinant Factor IX Coagulation
• ReFacto · Hematology
  ReFacto is a recombinant antihemophilic factor (Factor VIII) that replaces deficient or dysfunctional clotting factor VIII to restore blood coagulation in hemophilia A patients.
• rhIL-11
• Sirolimus+MMF or MPS or AZA+Steroid · Immunology / Transplantation
  This combination regimen suppresses T-cell proliferation and antibody production through mTOR inhibition (sirolimus) and inosine monophosphate dehydrogenase inhibition (MMF/MPS/AZA), used to prevent organ rejection.
• sulphasalazine (SSZ) · Gastroenterology / Immunology
  Sulphasalazine is a prodrug that is cleaved by colonic bacteria into 5-aminosalicylic acid and sulfapyridine, with the 5-ASA component exerting local anti-inflammatory effects in the colon.
• Third generation cephalosporins · Infectious Disease
  Third-generation cephalosporins inhibit bacterial cell wall synthesis by binding to penicillin-binding proteins and blocking cross-linking of peptidoglycan.
• Tibolone (Livial) · Endocrinology / Menopause
  Tibolone is a synthetic steroid that acts as a selective tissue estrogenic activity regulator (STEAR), providing estrogenic, progestagenic, and androgenic effects to alleviate menopausal symptoms.
• Totelle®

Phase 3 pipeline

• 23vPS · Immunology / Infectious Disease
  23vPS is a 23-valent pneumococcal polysaccharide vaccine that stimulates the immune system to produce antibodies against 23 serotypes of Streptococcus pneumoniae.
• 7vPnC · Infectious Diseases
  7vPnC is a vaccine that protects against meningococcal disease caused by serogroups B and Y.
• ATRA plus 6-MP and MTX · Oncology
  This combination uses ATRA to differentiate leukemic cells while 6-MP and MTX provide cytotoxic chemotherapy to eliminate rapidly dividing cancer cells.
• Bazedoxifene Acetate (TSE-424) · Bone Health / Osteoporosis
  Bazedoxifene is a selective estrogen receptor modulator (SERM) that acts as an estrogen agonist in bone and lipid metabolism while functioning as an antagonist in breast and uterine tissue.
• bazedoxifene BZA-20 · Osteoporosis
  Bazedoxifene acts as a selective estrogen receptor modulator (SERM) with agonist activity on the estrogen receptor beta and antagonist activity on the estrogen receptor alpha.
• bifeprunox, olanzapine · Psychiatry
  Bifeprunox is a selective dopamine D2 receptor antagonist and serotonin 5-HT2A receptor antagonist, and olanzapine is a serotonin 5-HT2A receptor antagonist and a dopamine D2 receptor antagonist.
• Cyclosporin or tacrolimus · Immunology
  Cyclosporin and tacrolimus are calcineurin inhibitors that suppress T-cell activation by blocking the transcription of pro-inflammatory cytokines.
• desvenlafaxine SR · Depression, Anxiety
  Desvenlafaxine SR is a serotonin-norepinephrine reuptake inhibitor (SNRI) that increases the levels of serotonin and norepinephrine in the brain.
• DVS-233 SR · Psychiatry / Mental Health
  DVS-233 SR is a sustained-release formulation of venlafaxine, a serotonin-norepinephrine reuptake inhibitor (SNRI) that increases synaptic levels of serotonin and norepinephrine by blocking their reuptake.
• effervescent ibuprofen tablets
• Pantoprazole for approximately 9 weeks · Gastroenterology
  Pantoprazole irreversibly inhibits the proton pump in gastric parietal cells, reducing gastric acid secretion.
• Pentavac · Other
• PVC (twice weekly) · Cardiovascular
  PVC works by blocking the action of certain electrical signals in the heart, helping to regulate its rhythm.
• rFIX · Hematology
  rFIX is a recombinant human coagulation factor IX that replaces deficient or dysfunctional Factor IX to restore blood clotting ability in hemophilia B patients.
• rFIX-R · Hematology
  rFIX-R is a recombinant coagulation factor IX used to treat bleeding episodes in patients with hemophilia B.
• Sirolimus (Rapamune®) · Immunology, Oncology
  Sirolimus inhibits mTOR (mammalian target of rapamycin), a key signaling protein that controls cell growth and proliferation.
• vancomycin with aztreonam

Phase 2 pipeline

• Bazedoxifene and conjugated estrogens · Women's Health / Endocrinology
  Bazedoxifene is a selective estrogen receptor modulator (SERM) that provides estrogen-like benefits in bone and lipid metabolism while blocking estrogen effects in breast tissue, combined with conjugated estrogens for menopausal symptom relief.
• EKB-569 · Oncology
  EKB-569 is an epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor.
• glycopeptide · Metabolic
• HCV 796
• ILV-094
• IMA-638
• lecozotan SR
• MAC-321
• Methotrexate plus ERB-041 for 12 weeks
• SAM-531
• SRA-333
• TMI-005
• vancomycin-resistant enterococci and ESBL

Phase 1 pipeline

• AS-101
• BDDrFVII
• ERB-257
• GAP-134
• GSI-953
• ILV-095
• marketed analgesic
• meningococcal B rLP2086 vaccine candidate
• MnB rLP2086
• MnB vaccine rLP8026
• MYO-029
• PRA-027
• Premarin® oral tablets
• SAM-531 and gemfibrozil
• SKI-606
• SRA-444

Competitive intelligence

For the full portfolio CI brief — phase mix, recent regulatory actions, upcoming PDUFA dates, patent timeline, class-overlap with competitors:

• Wyeth is now a wholly owned subsidiary of Pfizer portfolio CI brief
• Wyeth is now a wholly owned subsidiary of Pfizer pipeline updates RSS

Frequently asked questions about Wyeth is now a wholly owned subsidiary of Pfizer

Related

• 7-valent pneumococcal conjugate vaccine
• Advante · Other
• ceftriaxone plus metronidazole
• ceftriaxone sodium + metronidazole · Infectious Disease
• Effexor · Neuroscience
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