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DTwP-HepB-Hib-IPV vaccine
DTwP-HepB-Hib-IPV vaccine is a vaccine Biologic drug developed by Sanofi Pasteur, a Sanofi Company. It is currently in Phase 3 development for Primary immunization against diphtheria, tetanus, pertussis, hepatitis B, Haemophilus influenzae type b, and poliomyelitis in infants and children. Also known as: EasySix™.
This pentavalent vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, tetanus, pertussis, hepatitis B, Haemophilus influenzae type b, and poliomyelitis.
This pentavalent vaccine stimulates the immune system to produce antibodies and cellular immunity against diphtheria, tetanus, pertussis, hepatitis B, Haemophilus influenzae type b, and poliomyelitis. Used for Primary immunization against diphtheria, tetanus, pertussis, hepatitis B, Haemophilus influenzae type b, and poliomyelitis in infants and children.
At a glance
| Generic name | DTwP-HepB-Hib-IPV vaccine |
|---|---|
| Also known as | EasySix™ |
| Sponsor | Sanofi Pasteur, a Sanofi Company |
| Drug class | vaccine |
| Modality | Biologic |
| Therapeutic area | Immunology |
| Phase | Phase 3 |
Mechanism of action
DTwP-HepB-Hib-IPV is a combination vaccine containing inactivated toxoids (diphtheria and tetanus), whole-cell pertussis bacteria, hepatitis B surface antigen, Haemophilus influenzae type b conjugate, and inactivated poliovirus antigens. Upon administration, these antigens trigger both humoral (antibody) and cell-mediated immune responses, providing protection against these six infectious diseases. The vaccine is designed for primary immunization in infants and young children.
Approved indications
- Primary immunization against diphtheria, tetanus, pertussis, hepatitis B, Haemophilus influenzae type b, and poliomyelitis in infants and children
Common side effects
- Injection site reactions (pain, redness, swelling)
- Fever
- Irritability
- Drowsiness
Key clinical trials
- Study of a Quadrivalent Meningococcal Conjugate Vaccine (MenACYW Conjugate Vaccine) Given With Routine Pediatric Vaccines in Healthy Infants and Toddlers in India and the Republic of South Africa (PHASE3)
- Study of DTwP-HepB-Hib-IPV (SHAN6™) Vaccine Administered Concomitantly With Routine Pediatric Vaccines to Healthy Infants and Toddlers in Thailand (PHASE3)
- A Phase II/III Study to Evaluate the Immunogenicity, Safety and Lot-to-lot Consistency of LBVD, a Fully Liquid Hexavalent Diphtheria-tetanus-whole Cell Pertussis-hepatitis B-poliovirus-Haemophilus Influenzae Type b Conjugate (DTwP-HepB-IPV-Hib) Vaccine, in Healthy Infants as Primary Series (PHASE2, PHASE3)
- Clinical Study to Assess the Immunogenicity and Safety of Hexavalent Vaccine Containing Reduced Dose IPV (PHASE3)
- Study to Evaluate the Immunogenicity and Safety of LBVD(Hexavalent Vaccine), Given to Healthy Infants at Primary Series (PHASE2, PHASE3)
- Safety and Immunogenicity of Hexavalent Vaccine(DTwP-HepB-IPV-Hib) in Healthy Infants (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- DTwP-HepB-Hib-IPV vaccine CI brief — competitive landscape report
- DTwP-HepB-Hib-IPV vaccine updates RSS · CI watch RSS
- Sanofi Pasteur, a Sanofi Company portfolio CI
Frequently asked questions about DTwP-HepB-Hib-IPV vaccine
What is DTwP-HepB-Hib-IPV vaccine?
How does DTwP-HepB-Hib-IPV vaccine work?
What is DTwP-HepB-Hib-IPV vaccine used for?
Who makes DTwP-HepB-Hib-IPV vaccine?
Is DTwP-HepB-Hib-IPV vaccine also known as anything else?
What drug class is DTwP-HepB-Hib-IPV vaccine in?
What development phase is DTwP-HepB-Hib-IPV vaccine in?
What are the side effects of DTwP-HepB-Hib-IPV vaccine?
Related
- Drug class: All vaccine drugs
- Manufacturer: Sanofi Pasteur, a Sanofi Company — full pipeline
- Therapeutic area: All drugs in Immunology
- Indication: Drugs for Primary immunization against diphtheria, tetanus, pertussis, hepatitis B, Haemophilus influenzae type b, and poliomyelitis in infants and children
- Also known as: EasySix™
- Compare: DTwP-HepB-Hib-IPV vaccine vs similar drugs
- Pricing: DTwP-HepB-Hib-IPV vaccine cost, discount & access